Document Detail

Vitrectomy with peeling of the inner limiting membrane for treating diabetic macular edema.
MedLine Citation:
PMID:  16050416     Owner:  NLM     Status:  MEDLINE    
PURPOSE: to evaluate the results of pars plana vitrectomy with peeling of the inner limiting membrane (ILM stained with infracyanine green (IfCG) in 26 patients with diabetic macular edema, and to identify which factors are associated with a better postoperative visual outcome. PATIENTS AND METHODS: 26 patients with diabetic macular edema were included in the study. A pars plana vitrectomy with ILM peeling stained with IfCG was performed, in some cases combined with cataract surgery. In 22 patients the ILM was retained, examined with electron microscopy and compared with normal ILM's. Visual acuity and fundus examination were recorded several months after surgery. To determine which factors lead to the best postoperative results, patients were divided into different groups and compared. RESULTS: during surgery, a taut posterior hyaloid was found in 26 patients, which was successfully detached in all cases. ILM peeling within the vessel arcade succeeded in all patients. Postoperative examination showed improved visual acuity and decreased macular edema in 19 patients, unaltered visual acuity in 3 patients and decreased visual acuity in 4 patients. Comparison between different groups of patients revealed that young patients with recent vision loss and without previous macular laser treatment, had better postoperative results. Electron microscopical examination showed a more condensed ILM in diabetic patients, consisting of a layer of fine curled fibers. CONCLUSION: pars plana vitrectomy with peeling of the ILM stained with IfCG leads to good postoperative results in young diabetic patients with recent vision loss due to macular edema and without previous macular laser treatment.
D Kolacny; R Parys-Vanginderdeuren; A Van Lommel; P Stalmans
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  Bulletin de la Société belge d'ophtalmologie     Volume:  -     ISSN:  0081-0746     ISO Abbreviation:  Bull Soc Belge Ophtalmol     Publication Date:  2005  
Date Detail:
Created Date:  2005-07-29     Completed Date:  2005-10-26     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7505353     Medline TA:  Bull Soc Belge Ophtalmol     Country:  Belgium    
Other Details:
Languages:  eng     Pagination:  15-23     Citation Subset:  IM    
Dept. Ophthalmology UZLeuven, Leuven, Belgium.
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MeSH Terms
Diabetes Mellitus, Type 1 / complications
Diabetes Mellitus, Type 2 / complications
Diabetic Retinopathy / etiology,  surgery*
Epiretinal Membrane / pathology,  surgery*
Macular Edema / etiology,  surgery*
Middle Aged
Treatment Outcome
Visual Acuity
Vitrectomy / methods*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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