Document Detail

Vitrectomy for phacolytic glaucoma in a patient with homocystinuria.
MedLine Citation:
PMID:  10612517     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To determine the successful treatment of unilateral phacolytic glaucoma by vitrectomy and trabeculectomy in a patient with homocystinuria whose lens had dislocated into the vitreous at least 15 years earlier. METHODS: In a 32-year-old woman with homocystinuria, bilateral dislocation of the lens into the vitreous, and phacolytic glaucoma in her left eye a three-port pars plana vitrectomy was performed with the patient under general anesthesia. The lens was removed and a trabeculectomy fashioned. Special precautions for general anesthesia included preoperative aspirin and compression stockings for thromboembolic prophylaxis and intraoperative dextrose infusion, 5%, to maintain intravascular volume and prevent hypoglycemia. RESULTS: The intraocular pressure and uveitis resolved postoperatively with improvement in the visual acuity and intraocular pressure, which returned to normal without further treatment. CONCLUSIONS: Phacolytic glaucoma is best resolved by removal of the exciting lens material. Pars plana vitrectomy with the patient under general anesthesia can be carried out safely despite the risks traditionally associated with homocystinuria.
G T Smith; A N Vakalis; G P Brittain; A G Casswell
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  American journal of ophthalmology     Volume:  128     ISSN:  0002-9394     ISO Abbreviation:  Am. J. Ophthalmol.     Publication Date:  1999 Dec 
Date Detail:
Created Date:  1999-12-28     Completed Date:  1999-12-28     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370500     Medline TA:  Am J Ophthalmol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  762-3     Citation Subset:  AIM; IM    
The Sussex Eye Hospital, Brighton, England.
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MeSH Terms
Glaucoma / etiology,  surgery*
Homocystinuria / complications*
Intraocular Pressure
Lens Subluxation / complications,  surgery*,  ultrasonography
Visual Acuity

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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