Document Detail


Vitamins, minerals, and mood.
MedLine Citation:
PMID:  17723028     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In this article, the authors explore the breadth and depth of published research linking dietary vitamins and minerals (micronutrients) to mood. Since the 1920s, there have been many studies on individual vitamins (especially B vitamins and Vitamins C, D, and E), minerals (calcium, chromium, iron, magnesium, zinc, and selenium), and vitamin-like compounds (choline). Recent investigations with multi-ingredient formulas are especially promising. However, without a reasonable conceptual framework for understanding mechanisms by which micronutrients might influence mood, the published literature is too readily dismissed. Consequently, 4 explanatory models are presented, suggesting that mood symptoms may be expressions of inborn errors of metabolism, manifestations of deficient methylation reactions, alterations of gene expression by nutrient deficiency, and/or long-latency deficiency diseases. These models provide possible explanations for why micronutrient supplementation could ameliorate some mental symptoms.
Authors:
Bonnie J Kaplan; Susan G Crawford; Catherine J Field; J Steven A Simpson
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Psychological bulletin     Volume:  133     ISSN:  0033-2909     ISO Abbreviation:  Psychol Bull     Publication Date:  2007 Sep 
Date Detail:
Created Date:  2007-08-28     Completed Date:  2007-12-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0376473     Medline TA:  Psychol Bull     Country:  United States    
Other Details:
Languages:  eng     Pagination:  747-60     Citation Subset:  IM    
Copyright Information:
PsycINFO Database Record (c) 2007 APA, all rights reserved
Affiliation:
Department of Pediatrics, University of Calgary, Calgary, AB, Canada. kaplan@ucalgary.ca
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MeSH Terms
Descriptor/Qualifier:
Affect / physiology*
Brain / physiopathology
Deficiency Diseases / physiopathology,  psychology
Humans
Metabolism, Inborn Errors / physiopathology,  psychology
Micronutrients / physiology*
Minerals / metabolism*
Mood Disorders / physiopathology,  psychology
Vitamins / physiology*
Chemical
Reg. No./Substance:
0/Micronutrients; 0/Minerals; 0/Vitamins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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