Document Detail

Vitamins, minerals, essential fatty acids and colorectal cancer risk in the United Kingdom Dietary Cohort Consortium.
MedLine Citation:
PMID:  22139959     Owner:  NLM     Status:  MEDLINE    
The risk for colorectal cancer may be influenced by the dietary intake of various vitamins, minerals and essential fatty acids. We conducted a pooled analysis of dietary data collected using food diaries in seven prospective studies in the United Kingdom Dietary Cohort Consortium. Five hundred sixty-five cases of colorectal cancer were matched with 1,951 controls on study centre, age, sex and recruitment date. Dietary intakes of retinol, vitamin A, thiamin, riboflavin, vitamin B6, folate, vitamin B12, vitamin D, calcium, iron, magnesium, potassium, n - 6 fatty acids, n - 3 fatty acids and the ratio of n - 6 to n - 3 fatty acids were estimated and their associations with colorectal cancer examined using conditional logistic regression models, adjusting for exact age, height, weight, energy intake, alcohol intake, fiber intake, smoking, education, social class and physical activity. There were no statistically significant associations between colorectal cancer risk and dietary intake of any of the vitamins, minerals or essential fatty acids examined.
Timothy J Key; Paul N Appleby; Gabriel Masset; Eric J Brunner; Janet E Cade; Darren C Greenwood; Alison M Stephen; Diana Kuh; Amit Bhaniani; Natasha Powell; Kay-Tee Khaw
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Publication Detail:
Type:  Journal Article     Date:  2012-02-18
Journal Detail:
Title:  International journal of cancer. Journal international du cancer     Volume:  131     ISSN:  1097-0215     ISO Abbreviation:  Int. J. Cancer     Publication Date:  2012 Aug 
Date Detail:
Created Date:  2012-05-28     Completed Date:  2012-07-30     Revised Date:  2014-03-19    
Medline Journal Info:
Nlm Unique ID:  0042124     Medline TA:  Int J Cancer     Country:  United States    
Other Details:
Languages:  eng     Pagination:  E320-5     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 UICC.
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MeSH Terms
Cohort Studies
Colorectal Neoplasms / epidemiology*
Diet Surveys
Dietary Fats, Unsaturated / administration & dosage
Fatty Acids, Essential / administration & dosage*
Food Habits*
Great Britain / epidemiology
Middle Aged
Minerals / administration & dosage*
Risk Factors
Vitamins / administration & dosage*
Grant Support
11692//Cancer Research UK; G0401527//Medical Research Council; G0500300//Medical Research Council; G0800603//Medical Research Council; G1000143//Medical Research Council; MC_U105630924//Medical Research Council; MC_U105960384//Medical Research Council; MC_U123092720//Medical Research Council
Reg. No./Substance:
0/Dietary Fats, Unsaturated; 0/Fatty Acids, Essential; 0/Minerals; 0/Vitamins

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