Document Detail

Vitamin A in dietary supplements and fortified foods: too much of a good thing?
MedLine Citation:
PMID:  12963949     Owner:  NLM     Status:  MEDLINE    
Vitamin A consumption by many Americans is quite high, in part because of the consumption of fortified foods and the use of vitamin supplements. Most multivitamin supplements provide two or more times the recommended dietary allowance (RDA) for vitamin A because the daily value (DV) is based on 1968 and not current RDAs. Consumption of just one multivitamin often provides excessive vitamin A, the majority of it as preformed vitamin A esters. Given recent epidemiologic evidence that suggests a link between chronic intakes of vitamin A that exceed the RDA and hip fractures, it may be time to reexamine food and supplement fortification policies and to discontinue the clinical practice of prescribing two multivitamins to the elderly and other patients whose needs for certain micronutrients are high.
Kristina L Penniston; Sherry A Tanumihardjo
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of the American Dietetic Association     Volume:  103     ISSN:  0002-8223     ISO Abbreviation:  J Am Diet Assoc     Publication Date:  2003 Sep 
Date Detail:
Created Date:  2003-09-09     Completed Date:  2003-10-23     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  7503061     Medline TA:  J Am Diet Assoc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1185-7     Citation Subset:  AIM; IM    
University of Wisconsin Hospital and Clinics, Madison, WI 53706, USA.
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MeSH Terms
Dietary Supplements*
Food, Fortified*
Nutrition Policy
Nutritional Requirements
Nutritional Status
Nutritive Value
United States
Vitamin A / administration & dosage*,  adverse effects*
Grant Support
Reg. No./Substance:
11103-57-4/Vitamin A

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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