Document Detail


Vitamin A deficiency is associated with hepatitis C virus chronic infection and with unresponsiveness to interferon-based antiviral therapy.
MedLine Citation:
PMID:  23213086     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
CONCLUSION: A high percentage of patients with chronic HCV infection have serum vitamin A deficiency. This condition is associated with nonresponse to antiviral therapy.
Authors:
Davide Bitetto; Nadia Bortolotti; Edmondo Falleti; Sara Vescovo; Carlo Fabris; Giovanna Fattovich; Annarosa Cussigh; Sara Cmet; Ezio Fornasiere; Elisa Ceriani; Mario Pirisi; Pierluigi Toniutto
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Publication Detail:
Type:  Journal Article; Multicenter Study     Date:  2013-02-07
Journal Detail:
Title:  Hepatology (Baltimore, Md.)     Volume:  57     ISSN:  1527-3350     ISO Abbreviation:  Hepatology     Publication Date:  2013 Mar 
Date Detail:
Created Date:  2013-03-04     Completed Date:  2013-04-23     Revised Date:  2014-07-31    
Medline Journal Info:
Nlm Unique ID:  8302946     Medline TA:  Hepatology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  925-33     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 American Association for the Study of Liver Diseases.
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MeSH Terms
Descriptor/Qualifier:
Adult
Antiviral Agents / therapeutic use
Drug Resistance, Viral / genetics*
Female
Genetic Predisposition to Disease / epidemiology,  genetics
Genotype
Hepatitis C, Chronic / drug therapy*,  epidemiology*,  genetics
Humans
Interferon-alpha / therapeutic use*
Interleukins / genetics
Logistic Models
Male
Middle Aged
Polyethylene Glycols / therapeutic use*
Polymorphism, Single Nucleotide
Recombinant Proteins / therapeutic use
Risk Factors
Vitamin A / blood
Vitamin A Deficiency / blood,  epidemiology*
Vitamin D / blood
Vitamin D Deficiency / blood,  epidemiology
Vitamins / blood
Chemical
Reg. No./Substance:
0/Antiviral Agents; 0/IL28B protein, human; 0/Interferon-alpha; 0/Interleukins; 0/Polyethylene Glycols; 0/Recombinant Proteins; 0/Vitamins; 0/peginterferon alfa-2b; 11103-57-4/Vitamin A; 1406-16-2/Vitamin D

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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