Document Detail


Vitamin d and metabolic syndrome risk factors: evidence and mechanisms.
MedLine Citation:
PMID:  22059957     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The metabolic syndrome develops in an individual with any three of the following risk factors: obesity, diabetes, inflammation, hypertension, dyslipidemia, and thrombosis. Recent evidence suggests that vitamin D may play a role in the development of some of these risk factors. The metabolic syndrome is more common in western societies than the underdeveloped countries. Individuals in western societies usually consume a high calorie diet that lacks essential nutrients and, by virtue of being located in the northern hemisphere, they have limited sun exposures which restrict their vitamin D synthesis. Moreover, the lifestyle of these societies is considered sedentary. These dietary and environmental factors coupled with the sedentary lifestyle predispose them to metabolic syndrome risk factors. Active research revealed the role of vitamin D in the development of obesity, diabetes, inflammation, and hypertension. On the other hand, limited research has been done on the role of vitamin D in other risk factors such as dyslipidemia and thrombosis. The scientific community proposes to increase the current vitamin D fortification level in foods to reduce the risk factors of the metabolic syndrome.
Authors:
Atif B Awad; Lini Alappat; Michael Valerio
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Critical reviews in food science and nutrition     Volume:  52     ISSN:  1549-7852     ISO Abbreviation:  Crit Rev Food Sci Nutr     Publication Date:  2012  
Date Detail:
Created Date:  2011-11-08     Completed Date:  2012-03-15     Revised Date:  2012-03-22    
Medline Journal Info:
Nlm Unique ID:  8914818     Medline TA:  Crit Rev Food Sci Nutr     Country:  England    
Other Details:
Languages:  eng     Pagination:  103-12     Citation Subset:  IM    
Affiliation:
Department of Exercise and Nutrition Sciences, School of Public Health and Health Professions, University at Buffalo, New York, USA.
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MeSH Terms
Descriptor/Qualifier:
Humans
Metabolic Syndrome X / blood*,  complications*
Risk Factors
Vitamin D / blood*
Vitamin D Deficiency / complications*
Chemical
Reg. No./Substance:
1406-16-2/Vitamin D

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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