| Vitamin b(12) deficiency as a cause of delirium in a patient with spinal cord injury. | |
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MedLine Citation:
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PMID: 22032226 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Harrington AL, Dixon TM, Ho CH. Vitamin B(12) deficiency as a cause of delirium in a patient with spinal cord injury. A man with spinal cord injury (SCI) and multiple medical comorbidities had new-onset delirium during his 14th month of hospitalization. Diagnostic workup did not elicit an obvious etiology for mental status changes. Delirium persisted despite psychiatry intervention, and he was unable to be weaned from the ventilator because of prolonged agitation. Routine anemia workup revealed a possible untreated vitamin B(12) deficiency, although laboratory values were inconclusive. Empiric treatment with cyanocobalamin injections was initiated, and his delirium remarkably resolved after 3 weeks of treatment. We provide a concise review of the etiologies and varied clinical presentations of vitamin B(12) deficiency. As illustrated in this case, classic laboratory findings may not appear, and neurologic impairments from SCI can obscure the physical signs of deficiency, making diagnosis difficult. Empiric treatment may be indicated in cases of neuropsychiatric abnormalities not explained by other causes. |
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Authors:
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Amanda L Harrington; Thomas M Dixon; Chester H Ho |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Archives of physical medicine and rehabilitation Volume: 92 ISSN: 1532-821X ISO Abbreviation: Arch Phys Med Rehabil Publication Date: 2011 Nov |
Date Detail:
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Created Date: 2011-10-28 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 2985158R Medline TA: Arch Phys Med Rehabil Country: United States |
Other Details:
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Languages: eng Pagination: 1917-20 Citation Subset: AIM; IM |
Copyright Information:
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Copyright © 2011 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved. |
Affiliation:
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Department of Physical Medicine and Rehabilitation, University of Pittsburgh, Pittsburgh, PA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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