Document Detail

Vitamin A assay in burned patients.
MedLine Citation:
PMID:  1127768     Owner:  NLM     Status:  MEDLINE    
A study of serum vitamin A levels in burned patients at the Vancouver General Hospital (1972-1973) is reported in an attempt to relate hypovitaminosis A to acute stress erosions in the gastrointestinal tract. Thirty-one patients were studied, of whom 10 had moderate to severe burns. Vitamin A levels of normal males and females at the Vancouver General Hospital averaged at 35 mug/100 ml. Patients with burn indices of less than 12 did not show any significant fall in serum vitamin A levels. The fall of vitamin A levels was greater as the burn index increased, and the fall of vitamin A level was noticed within 48 hours postburn and returned to normal by the second week postburn. In patients with severe burns and gastrointestinal bleeding with stress ulcers, the serum vitamin A levels fell more profoundly (e.g., 18 mug/100 ml). Four patients with gastrointestinal bleeding were detected, of whom three had acute gastric erosions with low serum vitamin A levels. The possibility that hypovitaminosis A is a contributing factor in acute gastric erosions of the gastric mucosa in severely burned patients is suggested.
K Rai; A D Courtemanche
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of trauma     Volume:  15     ISSN:  0022-5282     ISO Abbreviation:  J Trauma     Publication Date:  1975 May 
Date Detail:
Created Date:  1975-07-14     Completed Date:  1975-07-14     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0376373     Medline TA:  J Trauma     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  419-24     Citation Subset:  AIM; IM    
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MeSH Terms
Burns / blood*,  complications
Middle Aged
Peptic Ulcer / blood*,  etiology
Peptic Ulcer Hemorrhage / blood
Time Factors
Vitamin A / blood*
Reg. No./Substance:
11103-57-4/Vitamin A

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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