Document Detail


Vitamin D status: a review with implications for the pelvic floor.
MedLine Citation:
PMID:  22415704     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Vitamin D is a micronutrient vital in calcium homeostasis and musculoskeletal function. Vitamin D insufficiency is a common variant of vitamin D deficiency that shows clinical signs of rickets and osteomalacia. The clinical significance of vitamin D insufficiency is being explored in several medical conditions. However, the most robust work suggests a role in musculoskeletal disease. The pelvic floor is a unique part of the body and the function of which is dependent on interrelationships between muscle, nerve, connective tissue, and bone. Pelvic floor disorders result when these relationships are disrupted. This paper reviews current knowledge regarding vitamin D nutritional status, the importance of vitamin D in muscle function, and how insufficient or deficient vitamin D levels may play a role in the function of the female pelvic floor.
Authors:
Candace Y Parker-Autry; Kathryn L Burgio; Holly E Richter
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Review     Date:  2012-03-14
Journal Detail:
Title:  International urogynecology journal     Volume:  23     ISSN:  1433-3023     ISO Abbreviation:  Int Urogynecol J     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-10-31     Completed Date:  2013-06-20     Revised Date:  2013-06-26    
Medline Journal Info:
Nlm Unique ID:  101567041     Medline TA:  Int Urogynecol J     Country:  England    
Other Details:
Languages:  eng     Pagination:  1517-26     Citation Subset:  IM    
Affiliation:
Division of Urogynecology and Pelvic Reconstructive Surgery, Department of Obstetrics and Gynecology, University of Alabama at Birmingham, 619 19th Street South, 176F, Suite 10382, Birmingham, AL 35249, USA. cautry@uabmc.edu
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MeSH Terms
Descriptor/Qualifier:
Female
Humans
Muscle, Skeletal / physiopathology
Nutritional Status
Pelvic Floor Disorders / etiology*,  physiopathology
Severity of Illness Index
Vitamin D / physiology*
Vitamin D Deficiency / complications*,  physiopathology
Grant Support
ID/Acronym/Agency:
2K24-DK068389/DK/NIDDK NIH HHS; K24 DK068389/DK/NIDDK NIH HHS
Chemical
Reg. No./Substance:
1406-16-2/Vitamin D
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