| Vitamin D status and metabolic syndrome in Asian Indians. | |
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MedLine Citation:
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PMID: 21060309 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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In this study, we aimed to estimate serum 25-hydroxy vitamin D (25-OH-D) in Asian Indians and test for association between 25-OH-D levels, insulin resistance (IR) and metabolic syndrome (MS). Serum 25-OH-D was measured in a cross-sectional sample of 441 Indians, aged 39.7±12.8 years (237 men and 204 women) with 27.9% prevalence of MS. Vitamin D insufficiency (12.5 to <50 nmol l(-1)) and hypovitaminosis D (50 to <100 nmol l(-1)) were present in 65.6 and 31.1% of participants, respectively. The 25-OH-D levels did not differ significantly between sexes (P=0.057). Multivariate regression analysis indicated a positive relationship between 25-OH-D and β-cell function (homeostasis model assessment (HOMA)-B; β=0.245, P=0.006), whereas regression coefficients for fasting glucose (β=0.262, P=0.794), insulin (β=-0.140, P=0.889) and HOMA-IR (β=-0.119, P=0.172) were insignificant. Sex-stratified analysis showed no linear trend for increasing quintiles of 25-OH-D with prevalence of MS or its components (P>0.05). Although highly prevalent, vitamin D insufficient status was not associated with MS or IR in Asian Indians of either sex. |
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Authors:
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V Majumdar; D Nagaraja; R Christopher |
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Publication Detail:
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Type: Journal Article Date: 2010-11-09 |
Journal Detail:
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Title: International journal of obesity (2005) Volume: 35 ISSN: 1476-5497 ISO Abbreviation: Int J Obes (Lond) Publication Date: 2011 Aug |
Date Detail:
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Created Date: 2011-08-10 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101256108 Medline TA: Int J Obes (Lond) Country: England |
Other Details:
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Languages: eng Pagination: 1131-4 Citation Subset: IM |
Affiliation:
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Department of Neurochemistry, National Institute of Mental Health and Neuro Sciences, Bangalore, India. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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