Document Detail


Vitamin D status in Chinese pregnant women and their newborns in Beijing and their relationships to birth size.
MedLine Citation:
PMID:  23174124     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
OBJECTIVE: To evaluate the prevalence of vitamin D deficiency in pregnant women and their newborns in Beijing, China and the influence of vitamin D deficiency on birth size. DESIGN: A cross-sectional study. SETTING: Data were collected from pregnant women who delivered during April to May 2010 at 306 Hospital of PLA in Beijing, China. SUBJECTS: Participants in the study were seventy healthy nulliparous pregnant women with singleton pregnancies who delivered healthy babies at full term and their newborns. RESULTS: Severe vitamin D deficiency (25-hydroxyvitamin D (25(OH)D) < 25 nmol/l) was detected in 54·5 % of mothers and 46·6 % of newborns. Neither mothers nor newborns had serum 25(OH)D concentrations that reached the normal level (>75 nmol/l). The concentration of 25(OH)D in mothers was positively correlated with that in cord blood (r = 0·89, P < 0·001). Newborns of mothers with severe vitamin D deficiency had lower birth length and birth weight. The head circumference and birth weight were lower in vitamin D-deficient newborns. CONCLUSIONS: The study indicates that pregnant women and neonates residing in Beijing are at high risk of vitamin D deficiency. Neonatal 25(OH)D concentrations are dependently related to maternal 25(OH)D levels. Maternal and neonatal vitamin D status influences newborn size.
Authors:
Shu Jun Song; Shaoyan Si; Junli Liu; Xingming Chen; Ling Zhou; Guiyue Jia; Genlan Liu; Yujing Niu; Jie Wu; Wenying Zhang; Jianzhong Zhang
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-7-16
Journal Detail:
Title:  Public health nutrition     Volume:  -     ISSN:  1475-2727     ISO Abbreviation:  Public Health Nutr     Publication Date:  2012 Jul 
Date Detail:
Created Date:  2012-11-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9808463     Medline TA:  Public Health Nutr     Country:  -    
Other Details:
Languages:  ENG     Pagination:  1-6     Citation Subset:  -    
Affiliation:
1 Department of Pathology and Experimental Medicine, 306 Hospital of PLA, Chao Yang District, Beijing 100101, People's Republic of China.
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