| Vitamin D status in Chinese pregnant women and their newborns in Beijing and their relationships to birth size. | |
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MedLine Citation:
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PMID: 23174124 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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OBJECTIVE: To evaluate the prevalence of vitamin D deficiency in pregnant women and their newborns in Beijing, China and the influence of vitamin D deficiency on birth size. DESIGN: A cross-sectional study. SETTING: Data were collected from pregnant women who delivered during April to May 2010 at 306 Hospital of PLA in Beijing, China. SUBJECTS: Participants in the study were seventy healthy nulliparous pregnant women with singleton pregnancies who delivered healthy babies at full term and their newborns. RESULTS: Severe vitamin D deficiency (25-hydroxyvitamin D (25(OH)D) < 25 nmol/l) was detected in 54·5 % of mothers and 46·6 % of newborns. Neither mothers nor newborns had serum 25(OH)D concentrations that reached the normal level (>75 nmol/l). The concentration of 25(OH)D in mothers was positively correlated with that in cord blood (r = 0·89, P < 0·001). Newborns of mothers with severe vitamin D deficiency had lower birth length and birth weight. The head circumference and birth weight were lower in vitamin D-deficient newborns. CONCLUSIONS: The study indicates that pregnant women and neonates residing in Beijing are at high risk of vitamin D deficiency. Neonatal 25(OH)D concentrations are dependently related to maternal 25(OH)D levels. Maternal and neonatal vitamin D status influences newborn size. |
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Authors:
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Shu Jun Song; Shaoyan Si; Junli Liu; Xingming Chen; Ling Zhou; Guiyue Jia; Genlan Liu; Yujing Niu; Jie Wu; Wenying Zhang; Jianzhong Zhang |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-7-16 |
Journal Detail:
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Title: Public health nutrition Volume: - ISSN: 1475-2727 ISO Abbreviation: Public Health Nutr Publication Date: 2012 Jul |
Date Detail:
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Created Date: 2012-11-23 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9808463 Medline TA: Public Health Nutr Country: - |
Other Details:
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Languages: ENG Pagination: 1-6 Citation Subset: - |
Affiliation:
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1 Department of Pathology and Experimental Medicine, 306 Hospital of PLA, Chao Yang District, Beijing 100101, People's Republic of China. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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