Document Detail


Vitamin D status and hyperparathyroisism in postmenopausal osteoporotic patients in Cipto Mangunkusumo hospital Jakarta.
MedLine Citation:
PMID:  18560026     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
AIM: to determine the profile of vitamin D and parathyroid hormone (PTH) and the proportion of vitamin D inadequacy in a population of postmenopausal osteoporotic patients from a rheumatologic outpatient clinic. METHODS: a cross sectional study was conducted between October and December 2006 in the Rheumatology Clinic, Cipto Mangunkusumo Hospital with osteoporosis confirmed by bone mineral densitometry (T score less than -2.5 at the lumbar spine or hip). Patients were excluded if there was a history of oral glucocorticoid treatment within 30 days, vitamin D supplementation, and have renal and/or liver function impairments. Forty-two postmenopausal osteoporotic patients aged 51-77 years old who had been postmenopausal for 5-28 years were included in this study. Vitamin D inadequacy was defined as the plasma levels of 25(OH)D less than 50 nmol/L whereas hyperparathyroidism was defined as the PTH level more than 69 pg/dL. RESULTS: vitamin D inadequacy was found in 61.9% of patients and 34.6% of them or 23.8% of total patients were also having high PTH level. There was an inverse correlation between 25(OH)D with PTH levels and positive correlation between duration of menopause and PTH level. Vitamin D inadequacy is common (61.9%) in postmenopausal osteoporotic patients who visited Rheumatology outpatient clinic of Cipto Mangunkusumo Hospital Jakarta. CONCLUSION: the low concentration of 25(OH)D was correlated with PTH level and duration of menopause. This finding should be confirmed in a larger epidemiological study, either hospital-or community-based to assess vitamin D status among postmenopausal women in Indonesia.
Authors:
Sumariyono Sarmidi; Bambang Setiyohadi; Suryo Anggoro KW
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta medica Indonesiana     Volume:  40     ISSN:  0125-9326     ISO Abbreviation:  Acta Med Indones     Publication Date:  2008 Apr 
Date Detail:
Created Date:  2008-06-18     Completed Date:  2009-02-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7901042     Medline TA:  Acta Med Indones     Country:  Indonesia    
Other Details:
Languages:  eng     Pagination:  69-73     Citation Subset:  IM    
Affiliation:
Department of Internal Medicine, Faculty of Medicine-dr. Cipto Mangunkusumo Hospital, Jl. Diponegoro no. 71 Jakarta.
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MeSH Terms
Descriptor/Qualifier:
Aged
Calcium / blood*
Cross-Sectional Studies
Female
Humans
Hyperparathyroidism / blood*,  complications
Indonesia / epidemiology
Middle Aged
Nutritional Status*
Osteoporosis, Postmenopausal / blood*,  complications,  epidemiology
Parathyroid Hormone / blood*
Risk Factors
Vitamin D / blood*
Chemical
Reg. No./Substance:
0/Parathyroid Hormone; 1406-16-2/Vitamin D; 7440-70-2/Calcium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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