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Vitamin D levels in Swiss multiple sclerosis patients.
MedLine Citation:
PMID:  21541856     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
BACKGROUND: Vitamin D levels have not been previously published for Swiss multiple sclerosis (MS) patients. An association between vitamin D status and disease activity in MS has been suggested.
AIM: To define 25-hydroxy-vitamin D (25(OH)D) levels in Swiss multiple sclerosis patients.
METHOD: Cross sectional case control study.
RESULTS: 25(OH)D levels of 80 patients (76.3% female, mean age 37.9 ± 10.6 years, mean Expanded Disability Status Scale (EDSS) 2.6 ± 1.2) were collected. Mean levels of 25(OH)D were 57.0 ± 29.7 nmol/l (range 18-175 nmol/l) in all patients. A total of 21.3% of patients had levels ≤37 nmol/l and 75% had levels ≤70 nmol/l. 25(OH)D levels in patients with previous high disease activity were 52.8 ± 23.1 nmol/l versus 58.9 ± 32.3 nmol/l in the low disease activity group (p = 0.4).
CONCLUSION: The prevalence of 25(OH)D deficiency was high in Swiss MS patients.
Authors:
M Yildiz; B Tettenborn; N Putzki
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Publication Detail:
Type:  Journal Article     Date:  2011-05-03
Journal Detail:
Title:  Swiss medical weekly     Volume:  141     ISSN:  1424-3997     ISO Abbreviation:  Swiss Med Wkly     Publication Date:  2011  
Date Detail:
Created Date:  2011-05-04     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100970884     Medline TA:  Swiss Med Wkly     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  w13192     Citation Subset:  IM    
Affiliation:
Department of Neurology, Multiple Sclerosis Outpatient Clinic, Cantonal Hospital St. Gallen, Rorschacher Strasse 95, 9000 St. Gallen, CH. yildizmur@yahoo.com.
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