Document Detail


Vitamin D deficiency and type 2 diabetes.
MedLine Citation:
PMID:  20065337     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Type 2 diabetes is a major public health problem, accounting for significant premature mortality and morbidity. The growth in prevalence of the condition appears to be closely linked with obesity. Over the last 5 years, a number of large observational studies have suggested an association between the onset of type 2 diabetes and Vitamin D deficiency. Vitamin D has important effects on insulin action, and may impact on a number of pathways which may be of importance in the development of type 2 diabetes. This article reviews the evidence linking Vitamin D deficiency in the pathogenesis of type 2 diabetes, and suggests areas for urgent further research to determine whether Vitamin D replacement has a role in the prevention of type 2 diabetes.
Authors:
Zehra Ozfirat; Tahseen A Chowdhury
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Postgraduate medical journal     Volume:  86     ISSN:  1469-0756     ISO Abbreviation:  Postgrad Med J     Publication Date:  2010 Jan 
Date Detail:
Created Date:  2010-01-12     Completed Date:  2010-03-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0234135     Medline TA:  Postgrad Med J     Country:  England    
Other Details:
Languages:  eng     Pagination:  18-25; quiz 24     Citation Subset:  IM    
Affiliation:
Department of Diabetes and Metabolism, The Royal London Hospital, Whitechapel, London, UK.
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MeSH Terms
Descriptor/Qualifier:
Diabetes Mellitus, Type 2 / etiology*
Epidemiologic Methods
Humans
Insulin Resistance / physiology
Seasons
Vitamin D Deficiency / complications*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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