| Vitamin D deficiency in cirrhosis relates to liver dysfunction rather than aetiology. | |
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MedLine Citation:
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PMID: 21412501 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIM: To examine the vitamin D status in patients with alcoholic cirrhosis compared to those with primary biliary cirrhosis. METHODS: Our retrospective case series comprised 89 patients with alcoholic cirrhosis and 34 patients with primary biliary cirrhosis who visited our outpatient clinic in 2005 and underwent a serum vitamin D status assessment. RESULTS: Among the patients with alcoholic cirrhosis, 85% had serum vitamin D levels below 50 nmol/L and 55% had levels below 25 nmol/L, as compared to 60% and 16% of the patients with primary biliary cirrhosis, respectively (P < 0.001). In both groups, serum vitamin D levels decreased with increasing liver disease severity, as determined by the Child-Pugh score. CONCLUSION: Vitamin D deficiency in cirrhosis relates to liver dysfunction rather than aetiology, with lower levels of vitamin D in alcoholic cirrhosis than in primary biliary cirrhosis. |
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Authors:
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Mikkel Malham; Søren Peter Jørgensen; Peter Ott; Jørgen Agnholt; Hendrik Vilstrup; Mette Borre; Jens F Dahlerup |
Publication Detail:
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Type: Case Reports; Comparative Study; Journal Article |
Journal Detail:
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Title: World journal of gastroenterology : WJG Volume: 17 ISSN: 1007-9327 ISO Abbreviation: World J. Gastroenterol. Publication Date: 2011 Feb |
Date Detail:
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Created Date: 2011-03-17 Completed Date: 2011-07-21 Revised Date: 2011-07-26 |
Medline Journal Info:
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Nlm Unique ID: 100883448 Medline TA: World J Gastroenterol Country: China |
Other Details:
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Languages: eng Pagination: 922-5 Citation Subset: IM |
Affiliation:
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Department of Medicine V (Hepatology and Gastroenterology), Aarhus University Hospital, DK-8000, Aarhus C, Denmark. mikkel.malham@gmail.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Humans Liver / physiopathology* Liver Cirrhosis, Alcoholic / blood, complications*, physiopathology Liver Cirrhosis, Biliary / blood, complications*, physiopathology Prevalence Retrospective Studies Risk Factors Vitamin D / blood Vitamin D Deficiency / epidemiology, etiology* |
| Chemical | |
Reg. No./Substance:
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1406-16-2/Vitamin D |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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