Document Detail


Vitamin D and asthma.
MedLine Citation:
PMID:  22928069     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Asthma, one of the most prevalent diseases affecting people worldwide, is a chronic respiratory disease characterized by heightened airway inflammation, airway hyperresponsiveness and airflow obstruction in response to specific triggers. While the specific mechanisms responsible for asthma are not well understood, changing environmental factors associated with urban lifestyles may underlie the increased prevalence of the disorder. Vitamin D is of particular interest in asthma since vitamin D concentrations decrease with increased time spent indoors, decreased exposure to sunlight, less exercise, obesity, and inadequate calcium intake. Additionally, a growing body of literature suggests that there is a relationship between vitamin D status and respiratory symptoms, presumably through immunomodulatory effects of vitamin D. This review discusses vitamin D as it relates to asthma across the age spectrum, with a focus on human studies.
Authors:
Sheena D Brown; H Hardie Calvert; Anne M Fitzpatrick
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Dermato-endocrinology     Volume:  4     ISSN:  1938-1980     ISO Abbreviation:  Dermatoendocrinol     Publication Date:  2012 Apr 
Date Detail:
Created Date:  2012-08-28     Completed Date:  2012-10-02     Revised Date:  2014-03-19    
Medline Journal Info:
Nlm Unique ID:  101495367     Medline TA:  Dermatoendocrinol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  137-45     Citation Subset:  -    
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Descriptor/Qualifier:
Grant Support
ID/Acronym/Agency:
R01 NR012021/NR/NINR NIH HHS
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