| Vitamin D as adjunctive therapy in refractory pulmonary tuberculosis: a case report. | |
| | |
MedLine Citation:
|
PMID: 19434014 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Vitamin D regulates calcium homeostasis in the body and may play a major role in regulating immune responses to tuberculosis (TB). Pilot studies suggest that vitamin D supplementation may improve outcomes in pulmonary TB (PTB), but clinical evidence using vitamin D in TB treatment is limited. We present a case of vitamin D deficiency in a woman with refractory drug-susceptible PTB. Antituberculous therapy and the correction of vitamin D deficiency resulted in clinical and microbiologic improvement at month 13 of her treatment. The basis for vitamin D/TB interactions and a brief literature review are discussed. Data from controlled trials are needed to evaluate the efficacy of vitamin D as adjunctive TB therapy. |
| | |
Authors:
|
Alexandra V Yamshchikov; Alawode Oladele; Michael K Leonard; Henry M Blumberg; Thomas R Ziegler; Vin Tangpricha |
Related Documents
:
|
8305774 - Fluosol: therapeutic failure in severe anemia. 3776984 - Failure to diagnose anemia in medical inpatients. is the traditional diagnosis of anemi... 11302404 - Life-threatening eosinophilic pleuropericardial effusion related to vitamins b5 and h. 21149114 - Unilateral cataracts: is successful amblyopia therapy compatible with binocular vision? 385584 - Psychiatric presentation of jakob-creutzfeldt disease. 17682984 - A multistate outbreak of serratia marcescens bloodstream infection associated with cont... |
Publication Detail:
|
Type: Case Reports; Journal Article; Research Support, N.I.H., Extramural |
Journal Detail:
|
Title: Southern medical journal Volume: 102 ISSN: 1541-8243 ISO Abbreviation: South. Med. J. Publication Date: 2009 Jun |
Date Detail:
|
Created Date: 2011-03-01 Completed Date: 2011-04-22 Revised Date: 2011-09-26 |
Medline Journal Info:
|
Nlm Unique ID: 0404522 Medline TA: South Med J Country: United States |
Other Details:
|
Languages: eng Pagination: 649-52 Citation Subset: AIM; IM |
Affiliation:
|
Division of Infectious Diseases, Department of Medicine, Emory University-School of Medicine, Atlanta, GA 30303, USA. ayamshc@emory.edu |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Female Humans Middle Aged Tuberculosis, Pulmonary / complications, drug therapy* Vitamin D / therapeutic use* Vitamin D Deficiency / complications, drug therapy Vitamins / therapeutic use* |
| Grant Support | |
ID/Acronym/Agency:
|
K23 AR054334/AR/NIAMS NIH HHS; K23 AR054334-03/AR/NIAMS NIH HHS; K23 AR054334-04/AR/NIAMS NIH HHS; K24 RR023356/RR/NCRR NIH HHS; T32DK007298/DK/NIDDK NIH HHS |
| Chemical | |
Reg. No./Substance:
|
0/Vitamins; 1406-16-2/Vitamin D |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: In the lymelight: law and clinical practice guidelines.
Next Document: RIFLE Criteria Accurately Identifies Renal Dysfunction and Renal Failure in Elderly Patients with Up...