| Vitamin D status of morbidly obese bariatric surgery patients. | |
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MedLine Citation:
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PMID: 20850786 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Abnormal vitamin D levels are common in bariatric surgery patients. The incidence of deficiencies and the response to therapy is not accurately delineated. The purpose of this study was to define the vitamin D status of patients who undergo either a malabsorptive (gastric bypass) or restrictive (adjustable gastric band) bariatric surgery both prior to and after surgery. METHODS: A retrospective analysis was performed on patients to undergo bariatric surgery from July 2002 to February 2007. Serum levels of vitamin D (Vit D), parathyroid hormone (PTH), and calcium were analyzed. RESULTS: Mean patient age was 45 y; 82% of patients were women. Of 127 total patients, 84% were Vit D deficient preoperatively. These patients had a higher preoperative body mass index (BMI) than those with normal Vit D levels on initial assessment (BMI 44 versus 50 kg/m(2), P < 0.01). A correlation was found between preoperative BMI and Vit D (r(2) = 0.12, P < 0.01) and PTH levels (r(2) = 0.07, P < 0.01). One year following gastric bypass surgery, 20% of patients with elevated PTH levels had normal Vit D levels. The incidence of observed deficiencies for adjustable gastric band versus gastric bypass did not differ statistically at any interval. CONCLUSIONS: Morbidly obese patients seeking bariatric surgery are often deficient in Vit D, a fact that should be accounted for when evaluating the impact of bariatric surgery on Vit D levels. Elevated BMI and increasing degrees of obesity may be risk factors for both Vit D deficiency and secondary hyperparathyroidism. Despite normal Vit D levels, some gastric bypass patients continue to show elevated levels of PTH. |
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Authors:
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Emily Fish; Gretchen Beverstein; Diane Olson; Susan Reinhardt; Michael Garren; Jon Gould |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2010-09-08 |
Journal Detail:
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Title: The Journal of surgical research Volume: 164 ISSN: 1095-8673 ISO Abbreviation: J. Surg. Res. Publication Date: 2010 Dec |
Date Detail:
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Created Date: 2010-11-24 Completed Date: 2010-12-22 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0376340 Medline TA: J Surg Res Country: United States |
Other Details:
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Languages: eng Pagination: 198-202 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 Elsevier Inc. All rights reserved. |
Affiliation:
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Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53792, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Bariatric Surgery Body Mass Index Calcium / blood, deficiency Female Follow-Up Studies Gastric Bypass Humans Male Middle Aged Obesity, Morbid / blood, complications, surgery* Parathyroid Hormone / blood Retrospective Studies Vitamin D / blood* Vitamin D Deficiency / blood, epidemiology |
| Chemical | |
Reg. No./Substance:
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0/Parathyroid Hormone; 1406-16-2/Vitamin D; 7440-70-2/Calcium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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