| Vitamin D: A D-Lightful Solution for Health. | |
| | |
MedLine Citation:
|
PMID: 21415774 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Throughout evolution, sunlight-produced vitamin D in the skin has been critically important for health. Vitamin D, known as the sunshine vitamin, is actually a hormone. Once it is produced in the skin or ingested from the diet, it is converted sequentially in the liver and kidneys to its biologically active form 1,25-dihydroxyvitamin D. This hormone interacts with its receptor in the small intestine to increase the efficiency of intestinal calcium and phosphate absorption for the maintenance of the skeleton throughout life. Vitamin D deficiency during the first few years of life results in a flattened pelvis, making it difficult for childbirth. Vitamin D deficiency causes osteopenia and osteoporosis, increasing risk of fracture. Essentially, every tissue and cell in the body has a vitamin D receptor. Therefore, vitamin D deficiency has been linked to increased risk for preeclampsia, requiring a cesarean section for birthing, multiple sclerosis, rheumatoid arthritis, types I and II diabetes, heart disease, dementia, deadly cancers, and infectious diseases. Therefore, sensible sun exposure along with vitamin D supplementation of at least 2000 IU/d for adults and 1000 IU/d for children is essential to maximize their health. |
| | |
Authors:
|
Michael F Holick |
Related Documents
:
|
2254984 - Assessing nutritional needs for the burned patient. 10565344 - Lipid supply and metabolism in infancy. 18641724 - About unsuspected potential determinants of obesity. 597774 - Loss of body fat during an arctic winter expedition. 22177404 - Social desirability, not dietary restraint, is related to accuracy of reported dietary ... 14998314 - An evaluation of the acceptability as forage of some nutritive and antinutritive compon... |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-3-16 |
Journal Detail:
|
Title: Journal of investigative medicine : the official publication of the American Federation for Clinical Research Volume: - ISSN: 1708-8267 ISO Abbreviation: - Publication Date: 2011 Mar |
Date Detail:
|
Created Date: 2011-3-18 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9501229 Medline TA: J Investig Med Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
From the Department of Medicine, Section of Endocrinology, Nutrition, and Diabetes, Vitamin D, Skin and Bone Research Laboratory, Boston University Medical Center, Boston, MA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Chromosome 9p21 Genetic Variants Are Associated With Myocardial Infarction But Not With Ischemic Str...
Next Document: Clinical Relevance of Autoantibody Detection in Lung Cancer.