| Vitamin C with metabolites reduce oxalate levels compared to ascorbic acid: a preliminary and novel clinical urologic finding. | |
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MedLine Citation:
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PMID: 19507407 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The incidence and prevalence of kidney stones are notable and are projected to increase over the next decade. Risk factors for kidney stones abound, but a prominent risk factor is hyperoxaluria, which has numerous etiologies, including vitamin C (ascorbic acid) dietary supplement intake. This randomized, double-blind, crossover study examined the effects of two different vitamin C formulations and found that vitamin C with metabolites (Ester-C) significantly reduced urine oxalate levels compared to ascorbic acid. This is a potential novel finding that requires further clinical evaluation. |
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Authors:
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Mark A Moyad; Maile A Combs; David C Crowley; Joshua E Baisley; Prachi Sharma; Angelica S Vrablic; Malkanthi Evans |
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Publication Detail:
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Type: Comparative Study; Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: Urologic nursing Volume: 29 ISSN: 1053-816X ISO Abbreviation: Urol Nurs Publication Date: 2009 Mar-Apr |
Date Detail:
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Created Date: 2009-06-10 Completed Date: 2009-08-05 Revised Date: 2010-04-26 |
Medline Journal Info:
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Nlm Unique ID: 8812256 Medline TA: Urol Nurs Country: United States |
Other Details:
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Languages: eng Pagination: 95-102 Citation Subset: N |
Affiliation:
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University of Michigan Medical Center, Department of Urology, Ann Arbor, MI, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Ascorbic Acid / pharmacology* Cross-Over Studies Dehydroascorbic Acid / pharmacology* Double-Blind Method Drug Combinations Female Humans Hyperoxaluria / prevention & control* Kidney Calculi / prevention & control* Male Oxalates / urine Threonine / pharmacology* |
| Chemical | |
Reg. No./Substance:
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0/Drug Combinations; 0/Oxalates; 490-83-5/Dehydroascorbic Acid; 50-81-7/Ascorbic Acid; 5743-27-1/calcium ascorbate; 72-19-5/Threonine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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