Document Detail

Vitamin C status in Iranian children with acute lymphoblastic leukemia: evidence for increased utilization.
MedLine Citation:
PMID:  17592383     Owner:  NLM     Status:  MEDLINE    
Vitamin C status and total antioxidant capacity (TAC) in children with acute lymphoblastic leukemia (ALL) was assessed in 28 hospitalized patients and 30 apparently healthy control subjects. It was determined that whereas vitamin C intake in patients with ALL was more than twice as much as in controls, plasma and urinary concentrations of vitamin C were more than 10 times and 2.5 times higher in controls than in the patients with ALL, respectively (P < 0.001). Accordingly, serum TAC levels in the patients with ALL were lower than in healthy subjects (P < 0.001). Vitamin C utilization is increased in children with ALL.
Tirang R Neyestani; Zahra Fereydouni; Sima Hejazi; Fatemeh Salehi-Nasab; Fariba Nateghifard; Mohsen Maddah; Majid Karandish
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of pediatric gastroenterology and nutrition     Volume:  45     ISSN:  1536-4801     ISO Abbreviation:  J. Pediatr. Gastroenterol. Nutr.     Publication Date:  2007 Jul 
Date Detail:
Created Date:  2007-06-26     Completed Date:  2007-07-10     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8211545     Medline TA:  J Pediatr Gastroenterol Nutr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  141-4     Citation Subset:  IM    
National Institute of Nutrition and Food Technology Researches, Shaheed Beheshti University of Medical Sciences, Tehran, Iran.
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MeSH Terms
Antioxidants / administration & dosage,  metabolism*
Ascorbic Acid / administration & dosage,  metabolism*
Case-Control Studies
Child, Preschool
Precursor Cell Lymphoblastic Leukemia-Lymphoma / metabolism*
Reg. No./Substance:
0/Antioxidants; 50-81-7/Ascorbic Acid

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