| Vitamin C in breast milk may reduce the risk of atopy in the infant. | |
| | |
MedLine Citation:
|
PMID: 15340369 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVE: To assess the effects of maternal dietary and supplement intake of vitamins C and E on breast milk antioxidant composition (vitamin C, alpha-tocopherol and beta-carotene) and their protective potential against the development of atopy in the infant. DESIGN, SUBJECTS AND METHODS: Mothers with atopic disease were recruited at the end of gestation and maternal sensitization was assessed by skin-prick testing. The 4-day food records of the mothers and breast milk samples were collected at the infants' age of 1 month. Infants' atopy was defined by the presence of atopic dermatitis during the first year of life and a positive skin-prick test reaction at 12 months of age (n=34). RESULTS: Maternal intake of vitamin C in diet but not as supplement was shown to determine the concentration of vitamin C in breast milk. A higher concentration of vitamin C in breast milk was associated with a reduced risk of atopy in the infant (OR=0.30; 95% CI 0.09-0.94; P=0.038), whereas alpha-tocopherol had no consistent relationship with atopy. The group at risk of suboptimal vitamin C supply from breast milk was identified as infants whose mothers suffer from food hypersensitivity. CONCLUSION: A maternal diet rich in natural sources of vitamin C during breastfeeding could reduce the risk of atopy in high-risk infants. |
| | |
Authors:
|
U Hoppu; M Rinne; P Salo-Väänänen; A-M Lampi; V Piironen; E Isolauri |
Related Documents
:
|
8102669 - Acute toxicity of vitamin a given with vaccines in infancy. 17103079 - Vitamin a and beta-carotene supply of women with gemini or short birth intervals: a pil... 12785689 - Hypophosphatemia associated with hypovitaminosis-d in speke's gazelles (gazella spekei). 7647149 - Activities of trypsin and lipase in duodenal aspirates of healthy preterm infants: effe... 15635999 - Damage of office supply, personal use items, and over-the-counter medical devices after... 8267479 - Hemofiltration modifies complement activation after extracorporeal circulation in infants. 14670769 - Factors relating to the infant's last sleep environment in sudden infant death syndrome... 10559699 - Season of birth in panic disorder. 2645979 - Neonatal nosocomial infections. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: European journal of clinical nutrition Volume: 59 ISSN: 0954-3007 ISO Abbreviation: Eur J Clin Nutr Publication Date: 2005 Jan |
Date Detail:
|
Created Date: 2004-12-16 Completed Date: 2005-04-08 Revised Date: 2012-09-10 |
Medline Journal Info:
|
Nlm Unique ID: 8804070 Medline TA: Eur J Clin Nutr Country: England |
Other Details:
|
Languages: eng Pagination: 123-8 Citation Subset: IM |
Affiliation:
|
Department of Paediatrics, University of Turku, Turku, Finland. ulla.hoppu@utu.fi |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Antioxidants / administration & dosage*, analysis Ascorbic Acid / administration & dosage*, analysis, immunology Breast Feeding Confidence Intervals Dermatitis, Atopic / epidemiology*, immunology Dietary Supplements Female Humans Infant Infant Food Infant Nutritional Physiological Phenomena* Infant, Newborn Maternal Nutritional Physiological Phenomena* Milk, Human / chemistry, immunology* Odds Ratio Pregnancy Risk Factors Skin Tests Vitamin E / administration & dosage*, analysis, immunology |
| Chemical | |
Reg. No./Substance:
|
0/Antioxidants; 1406-18-4/Vitamin E; 50-81-7/Ascorbic Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Dietary habits and nutritional biomarkers in Italian type 1 diabetes families: evidence of unhealthy...
Next Document: Body water distribution in severe obesity and its assessment from eight-polar bioelectrical impedanc...