| Vitamin C and cardiovascular risk factors. | |
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MedLine Citation:
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PMID: 1985405 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The concept that ascorbic acid (vitamin C) supplementation protects against coronary heart disease developed in the late 1970s when vitamin C intakes in industrialized nations were lower than at present. Supplementation was then shown to lower plasma total cholesterol and, among some elderly men, to raise high-density lipoprotein cholesterol. However, among people in initially good vitamin C nutriture, these effects are usually not seen. In five populations of essentially healthy people, blood pressure has been found to correlate negatively with vitamin C status. Recently, in a placebo-controlled, double-blinded study, extra ascorbic acid for 6 wk was observed to lower systolic and pulse pressure in a small group of borderline hypertensive subjects. |
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Authors:
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D L Trout |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: The American journal of clinical nutrition Volume: 53 ISSN: 0002-9165 ISO Abbreviation: Am. J. Clin. Nutr. Publication Date: 1991 Jan |
Date Detail:
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Created Date: 1991-02-01 Completed Date: 1991-02-01 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0376027 Medline TA: Am J Clin Nutr Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 322S-325S Citation Subset: AIM; IM |
Affiliation:
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Carbohydrate Nutrition Laboratory, US Department of Agriculture, Beltsville, MD 20705. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Age Factors Ascorbic Acid / blood, pharmacology, therapeutic use* Blood Pressure / drug effects Cholesterol / blood Cholesterol, HDL / blood Coronary Disease / prevention & control* Diabetes Mellitus / metabolism Humans Risk Factors Sex Factors Smoking / adverse effects |
| Chemical | |
Reg. No./Substance:
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0/Cholesterol, HDL; 50-81-7/Ascorbic Acid; 57-88-5/Cholesterol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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