Document Detail


Vitamin B12 in metformin-treated diabetic patients: a cross-sectional study in Brazil.
MedLine Citation:
PMID:  21390459     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
OBJECTIVE: The objective of this study was to evaluate the presence of vitamin B12 deficiency and the factors associated with serum vitamin B12 levels in a sample of metformin-treated Brazilian diabetic patients.
METHOD: Cross-sectional study.
RESULTS: 144 patients were included. Serum vitamin B12 levels were low (< 125 pmol/L) in 10 patients (6.9%) and possibly low (125 - 250 pmol/L) in 53 patients (36.8%). Serum vitamin B12 levels were negatively associated with age (B = -3.17; β= -0.171; p = 0.037) and duration of metformin use (B= -33.36; β= -0.161; p = 0.048), and positively associated with the estimated intake of vitamin B12 (B= 67.96; β= 0.249; p = 0.002).
CONCLUSION: The present findings suggest a high prevalence of vitamin B12 deficiency in metformin-treated diabetic patients. Older patients, patients in long term treatment with metformin and low vitamin B12 intake are probably more prone to this deficiency.
Authors:
Monique Nervo; Adriano Lubini; Fabiana Viegas Raimundo; Gustavo Adolpho Moreira Faulhaber; Carine Leite; Leonardo Moura Fischer; Tania Weber Furlanetto
Related Documents :
3438309 - Different responses of serum cationic trypsinogen to secretin and bombesin in normal su...
90969 - Urinary immunoreactive trypsin excretion: a non-invasive screening test for pancreatic ...
420999 - Prospective study of ultrasonography in chronic pancreatic disease.
1713669 - Pmn-elastase in comparison with crp, antiproteases, and ldh as indicators of necrosis i...
7317769 - Pulmonary function and fibrinogen metabolism in acute pancreatitis.
8875689 - Acute renal failure as a complication of acute pancreatitis.
24576299 - The impact of metabolic syndrome on serum total testosterone level in patients with ere...
12917229 - A study of the cough reflex in idiopathic pulmonary fibrosis.
3819219 - Seasonal increase of bronchial reactivity in allergic rhinitis.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Revista da Associação Médica Brasileira (1992)     Volume:  57     ISSN:  0104-4230     ISO Abbreviation:  Rev Assoc Med Bras     Publication Date:    2011 Jan-Feb
Date Detail:
Created Date:  2011-03-10     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9308586     Medline TA:  Rev Assoc Med Bras     Country:  Brazil    
Other Details:
Languages:  eng     Pagination:  46-9     Citation Subset:  IM    
Affiliation:
Internal Medicine Service, Hospital de Clínicas de Porto Alegre, Porto Alegre, RS.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Prevalence of hospital admission due to adverse drug reaction in Salvador, Bahia.
Next Document:  Overweight and abdominal fat in adult population of Teresina, PI.