| Vitamin B12 absorption capacity in healthy children. | |
| | |
MedLine Citation:
|
PMID: 3958854 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
B12 absorption was investigated in 47 healthy children aged 7 months to 15.8 years (median 4.9 years). The patients had either recovered from giardiasis, the post-gastroenteritis syndrome, or had celiac disease in remission (treated with a gluten-free diet). The B12 absorption was measured by a double-isotope technique using 57CoB12 and 51CrCl3, the latter being the inabsorbable marker. The radiation dose was minimal. The results were presented as fractional absorption of B12 (FAB12). Within the different age groups, the absorption test was performed by means of the following oral amounts of B12: 0- less than 1 year, 0.5 microgram; 1-3 years: 1.7 micrograms, 4-6 years, 2.5 micrograms; 7-10 years; 3.3 micrograms; and 11-15 years, 4.5 micrograms. When using these oral amounts of B12, the medians (and ranges) of FAB12 were found to be: 1-3 years (n = 18), 37% (16-80%); 4-6 years (n = 10), 27% (19-40%); 7-10 years (n = 9), 32% (21-44%); and 11-15 years (n = 8), 27% (19-59%). The FAB12 in two children aged 7 and 11 months was 31% and 32%, respectively. These results may be interpretated as reference values for B12 absorption in children. Further absorption tests were performed in seven children representing the four age groups from 1 to 15 years. When a high oral amount of B12 was given (i.e., three times the saturation dose), the FAB12 ranged from 0 to 20% (median 9%), whereas a low amount (i.e., one-ninth of the saturation dose) produced fractional absorptions from 65 to 82% (median 74%).(ABSTRACT TRUNCATED AT 250 WORDS) |
| | |
Authors:
|
K Hjelt; P A Krasilnikoff |
Related Documents
:
|
21691244 - Baseline estimates of diarrhea-associated mortality among united states children before... 17204974 - Effect of infections and environmental factors on growth and nutritional status in deve... 23319524 - Parental explicit heuristics in decision-making for children with life-threatening illn... 1030854 - The vitamin b1, b2 and b6 status of school children in two resettlement areas in northe... 9493744 - Heritability of poor language achievement among twins. 22150774 - Corneal parameters of six- to 12-year-old chinese children. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Journal of pediatric gastroenterology and nutrition Volume: 5 ISSN: 0277-2116 ISO Abbreviation: J. Pediatr. Gastroenterol. Nutr. Publication Date: 1986 Mar-Apr |
Date Detail:
|
Created Date: 1986-05-13 Completed Date: 1986-05-13 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 8211545 Medline TA: J Pediatr Gastroenterol Nutr Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 274-7 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adolescent Age Factors Child Child, Preschool Chlorides* Chromium / diagnostic use Chromium Compounds* Cobalt Radioisotopes / diagnostic use Humans Infant Intestinal Absorption* Vitamin B 12 / metabolism* |
| Chemical | |
Reg. No./Substance:
|
0/Chlorides; 0/Chromium Compounds; 0/Cobalt Radioisotopes; 10049-05-5/chromous chloride; 68-19-9/Vitamin B 12; 7440-47-3/Chromium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Reliability of a new technique for the determination of vitamin B12 absorption in children: single s...
Next Document: Folate nutrition is optimal in exclusively breast-fed infants but inadequate in some of their mother...