Document Detail


Vital signs and cognitive function are not affected by 23-sodium and 17-oxygen magnetic resonance imaging of the human brain at 9.4 T.
MedLine Citation:
PMID:  20578014     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To evaluate the effect of 23-sodium ((23)Na) and 17-oxygen ((17)O) magnetic resonance imaging (MRI) at 9.4 (T) on vital signs and cognitive function of the human brain. MATERIALS AND METHODS: Vital sign and cognitive function measurements from healthy volunteers (N = 14) positioned outside and at isocenter of a 9.4 T scanner before and after (23)Na and (17)O MRI were compared for changes due to exposure to the static magnetic field and to the gradient switching and radiofrequency radiation during MRI. RESULTS: Exposure to the 9.4 T static magnetic field and (23)Na and (17)O MRI at 105.92 MHz and 54.25 MHz, respectively, did not have a statistically significant (P > 0.05) effect on the vital signs or cognitive function of healthy normal adults. CONCLUSION: (23)Na and (17)O MRI of the human brain at 9.4 T does not have any readily demonstrated health risks reflected in vital signs or change in cognitive performance.
Authors:
Ian C Atkinson; Rachel Sonstegaard; Neil H Pliskin; Keith R Thulborn
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of magnetic resonance imaging : JMRI     Volume:  32     ISSN:  1522-2586     ISO Abbreviation:  J Magn Reson Imaging     Publication Date:  2010 Jul 
Date Detail:
Created Date:  2010-06-29     Completed Date:  2010-10-18     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9105850     Medline TA:  J Magn Reson Imaging     Country:  United States    
Other Details:
Languages:  eng     Pagination:  82-7     Citation Subset:  IM    
Copyright Information:
(c) 2010 Wiley-Liss, Inc.
Affiliation:
Center for Magnetic Resonance Research, University of Illinois at Chicago, Chicago, Illinois 60612, USA. ian@uic.edu
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MeSH Terms
Descriptor/Qualifier:
Adult
Analysis of Variance
Brain / radiation effects*
Cognition / radiation effects*
Female
Humans
Magnetic Resonance Imaging / methods*
Magnetics
Male
Middle Aged
Oxygen Isotopes / adverse effects*,  diagnostic use
Reference Values
Sodium Isotopes / adverse effects*,  diagnostic use
Vital Signs / radiation effects*
Young Adult
Chemical
Reg. No./Substance:
0/Oxygen Isotopes; 0/Sodium Isotopes

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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