Document Detail


Visualization of the small intestine using capsule endoscopy in healthy subjects.
MedLine Citation:
PMID:  17380402     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The actual extent of lumen visualized by capsule endoscopy has not been studied systematically. Volunteers were randomized to receive a bowel preparation (prep) consisting of an isotonic solution containing polyethylene glycol and simethicone. The prep (200 ml) was given 30 min before the capsule. The capsule was taken with 100 ml of prep and 100 ml of water; 100 ml of prep was given 45 and 75 min later. The control administration was 100 ml of water and no simethicone. Forty percent of all frames taken in the small bowel were examined and individually scored for circumference, bubbles, debris, and lighting. Nine volunteers were studied twice. Only 50% of the circumference is seen normally. The prep improved the circumference to 62.5% as well as decreasing luminal debris and bubbles and improving the lighting. We conclude that the prep solution improved small bowel visualization, however, improvements are still needed to optimize visualization.
Authors:
Akiko Shiotani; Antone R Opekun; David Y Graham
Publication Detail:
Type:  Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.     Date:  2007-02-16
Journal Detail:
Title:  Digestive diseases and sciences     Volume:  52     ISSN:  0163-2116     ISO Abbreviation:  Dig. Dis. Sci.     Publication Date:  2007 Apr 
Date Detail:
Created Date:  2007-03-23     Completed Date:  2007-05-24     Revised Date:  2007-12-03    
Medline Journal Info:
Nlm Unique ID:  7902782     Medline TA:  Dig Dis Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1019-25     Citation Subset:  AIM; IM    
Affiliation:
Department of Medicine, Michael E. DeBakey Veterans Affairs Medical Center, and Baylor College of Medicine, 2002 Holcombe Boulkevard, Houston, TX 77030, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Capsule Endoscopy*
Endoscopy, Gastrointestinal*
Female
Humans
Intestine, Small / anatomy & histology*
Male
Middle Aged
Polyethylene Glycols / administration & dosage
Grant Support
ID/Acronym/Agency:
DK 53659/DK/NIDDK NIH HHS; DK 56338/DK/NIDDK NIH HHS
Chemical
Reg. No./Substance:
0/Polyethylene Glycols

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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