Document Detail


Visual restoration in cortical blindness: insights from natural and TMS-induced blindsight.
MedLine Citation:
PMID:  16864478     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Unilateral damage to visual cortex of the parietal or occipital lobe can cause the patient to be unaware of contralesional visual information due to either hemispatial neglect or hemianopia. It is now known that both neglect and hemianopia result from the disruption of a dynamic interaction between cortical visual pathways and more phylogenetically primitive visual pathways to the midbrain. We consider the therapeutic implications of these cortical-subcortical interactions in the rehabilitation of hemianopia. We start with the pheonmenon of "blindsight", in which patients with hemianopia can be shown, by implicit measures of visual detection or discrimination, to process visual information without conscious awareness. Some variants of blindsight have been postulated to recruit subcortical processes, while others may reflect compensatory optimisation of processing of spared visual cortex. Both mechanisms may offer opportunities for innovative strategies for rehabilitation of visual field defects. We relate the neural mechanisms that have been proposed to underlie blindsight to those that have been suggested to underlie the recovery of visual function after rehabilitation. It is suggested that the similarity and overlap of the neural processes supporting blindsight and recovery of visual function might provide insights for effective rehabilitation strategies for restoring visual functions.
Authors:
Tony Ro; Robert Rafal
Related Documents :
24665018 - Developmental remodeling of corticocortical feedback circuits in ferret visual cortex.
24632468 - H2o2- or l-dopa-injured dopaminergic neurons trigger the release of soluble mediators t...
24110748 - Influence of active dendrites on firing patterns in a retinal ganglion cell model.
23439118 - Mtor inhibition ameliorates cognitive and affective deficits caused by disc1 knockdown ...
9708958 - Role of the premotor cortex in recovery from middle cerebral artery infarction.
10679768 - Endogenous igf-1 regulates the neuronal differentiation of adult stem cells.
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Neuropsychological rehabilitation     Volume:  16     ISSN:  0960-2011     ISO Abbreviation:  Neuropsychol Rehabil     Publication Date:  2006 Aug 
Date Detail:
Created Date:  2006-07-25     Completed Date:  2006-10-18     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  9112672     Medline TA:  Neuropsychol Rehabil     Country:  England    
Other Details:
Languages:  eng     Pagination:  377-96     Citation Subset:  IM    
Affiliation:
Department of Psychology, Rice University, Houston, TX, USA. tro@rice.edu
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Awareness / physiology
Blindness, Cortical / rehabilitation*
Functional Laterality / physiology
Hemianopsia / physiopathology,  rehabilitation
Humans
Recovery of Function / physiology*
Transcranial Magnetic Stimulation*
Vision, Ocular / physiology*,  radiation effects
Visual Cortex / physiopathology*
Visual Pathways / physiopathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  What do we mean by "conscious" and "aware"?
Next Document:  Self-awareness after acquired and traumatic brain injury.