Document Detail

Visual restoration in cortical blindness: insights from natural and TMS-induced blindsight.
MedLine Citation:
PMID:  16864478     Owner:  NLM     Status:  MEDLINE    
Unilateral damage to visual cortex of the parietal or occipital lobe can cause the patient to be unaware of contralesional visual information due to either hemispatial neglect or hemianopia. It is now known that both neglect and hemianopia result from the disruption of a dynamic interaction between cortical visual pathways and more phylogenetically primitive visual pathways to the midbrain. We consider the therapeutic implications of these cortical-subcortical interactions in the rehabilitation of hemianopia. We start with the pheonmenon of "blindsight", in which patients with hemianopia can be shown, by implicit measures of visual detection or discrimination, to process visual information without conscious awareness. Some variants of blindsight have been postulated to recruit subcortical processes, while others may reflect compensatory optimisation of processing of spared visual cortex. Both mechanisms may offer opportunities for innovative strategies for rehabilitation of visual field defects. We relate the neural mechanisms that have been proposed to underlie blindsight to those that have been suggested to underlie the recovery of visual function after rehabilitation. It is suggested that the similarity and overlap of the neural processes supporting blindsight and recovery of visual function might provide insights for effective rehabilitation strategies for restoring visual functions.
Tony Ro; Robert Rafal
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Neuropsychological rehabilitation     Volume:  16     ISSN:  0960-2011     ISO Abbreviation:  Neuropsychol Rehabil     Publication Date:  2006 Aug 
Date Detail:
Created Date:  2006-07-25     Completed Date:  2006-10-18     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  9112672     Medline TA:  Neuropsychol Rehabil     Country:  England    
Other Details:
Languages:  eng     Pagination:  377-96     Citation Subset:  IM    
Department of Psychology, Rice University, Houston, TX, USA.
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MeSH Terms
Awareness / physiology
Blindness, Cortical / rehabilitation*
Functional Laterality / physiology
Hemianopsia / physiopathology,  rehabilitation
Recovery of Function / physiology*
Transcranial Magnetic Stimulation*
Vision, Ocular / physiology*,  radiation effects
Visual Cortex / physiopathology*
Visual Pathways / physiopathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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