| Visual motion processing investigated using contrast agent-enhanced fMRI in awake behaving monkeys. | |
| | |
MedLine Citation:
|
PMID: 11719199 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
To reduce the information gap between human neuroimaging and macaque physiology and anatomy, we mapped fMRI signals produced by moving and stationary stimuli (random dots or lines) in fixating monkeys. Functional sensitivity was increased by a factor of approximately 5 relative to the BOLD technique by injecting a contrast agent (monocrystalline iron oxide nanoparticle [MION]). Areas identified as motion sensitive included V2, V3, MT/V5, vMST, FST, VIP, and FEF (with moving dots), as well as V4, TE, LIP, and PIP (with random lines). These regions sensitive for moving dots are largely in agreement with monkey single unit data and (except for V3A) with human fMRI results. Moving lines activate some regions that have not been previously implicated in motion processing. Overall, the results clarify the relationship between the motion pathway and the dorsal stream in primates. |
| | |
Authors:
|
W Vanduffel; D Fize; J B Mandeville; K Nelissen; P Van Hecke; B R Rosen; R B Tootell; G A Orban |
Related Documents
:
|
22570029 - Phototoxic action of light emitting diode in the in vitro viability of trichophyton rub... 21346139 - Zilpaterol hydrochloride supplementation has no effect on the shelf life of ground beef. 8594819 - On the relative contributions of motion energy and transparency to the perception of mo... 2487639 - Human horizontal optokinetic nystagmus elicited by the upper versus the lower visual fi... 16562639 - An oral tactile interface for blind navigation. 16643089 - A feature-tracking model simulates the motion direction bias induced by phase congruency. 17295279 - Toxicity of the quinalphos metabolite 2-hydroxyquinoxaline: growth inhibition, inductio... 17770309 - Photoperiodism in lemna: reversal of nightinterruption depends on color of the main pho... 9680719 - Refinement of a limit cycle oscillator model of the effects of light on the human circa... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Neuron Volume: 32 ISSN: 0896-6273 ISO Abbreviation: Neuron Publication Date: 2001 Nov |
Date Detail:
|
Created Date: 2001-11-23 Completed Date: 2002-01-03 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 8809320 Medline TA: Neuron Country: United States |
Other Details:
|
Languages: eng Pagination: 565-77 Citation Subset: IM |
Affiliation:
|
Laboratorium voor Neuro- en Psychofysiologie, Katholieke Universiteit Leuven, Campus Gasthuisberg, Herestraat 49, Belgium. wim.vanduffel@med.kuleuven.ac.be |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Awareness Behavior, Animal / physiology Brain Mapping / methods Contrast Media* Ferrosoferric Oxide Iron* Macaca mulatta Magnetic Resonance Imaging / methods*, standards Male Motion Perception / physiology* Oxides* Parietal Lobe / physiology Reproducibility of Results Sensitivity and Specificity Temporal Lobe / physiology Visual Cortex / physiology* |
| Chemical | |
Reg. No./Substance:
|
0/Contrast Media; 0/Oxides; 1317-61-9/Ferrosoferric Oxide; 7439-89-6/Iron |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Presynaptic kainate receptors in the hippocampus: slowly emerging from obscurity.
Next Document: Interaction with telencephalin and the amyloid precursor protein predicts a ring structure for prese...