Document Detail

Visual loss secondary to orbital apex invasion as the first manifestation of recurrent nasopharyngeal carcinoma.
MedLine Citation:
PMID:  19454949     Owner:  NLM     Status:  MEDLINE    
A 51-year-old white man was referred for evaluation of visual loss in the right eye caused by an apical orbital lesion. His medical history was positive for "lymphoepithelial carcinoma" of the nasopharynx successfully treated with radiotherapy 6 years previously. Cranial CT showed a diffuse orbital mass extending from the pterygopalatine fossa, infiltrating the inferior orbital fissure, the orbital apex, and the cranial cavity. Results from an incisional biopsy of the lesion were consistent with the diagnosis of nasopharyngeal carcinoma, nonkeratinizing lymphoepithelial variant of squamous cell carcinoma. The patient underwent stereotactic radiosurgery, which arrested the tumor progression. Orbitocranial recurrence of nasopharyngeal carcinoma is rare and ocular symptoms may be the first manifestation of the disease.
Francesco P Bernardini; J Oscar Croxatto; Giulio Fraternali Orcioni; Stefania Bianchi
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Ophthalmic plastic and reconstructive surgery     Volume:  25     ISSN:  1537-2677     ISO Abbreviation:  Ophthal Plast Reconstr Surg     Publication Date:    2009 May-Jun
Date Detail:
Created Date:  2009-05-20     Completed Date:  2009-08-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8508431     Medline TA:  Ophthal Plast Reconstr Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  248-50     Citation Subset:  IM    
Department of Ophthalmology, Ospedale Evangelico Internazionale, Genova, Italy.
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MeSH Terms
Carcinoma, Squamous Cell / complications*,  pathology,  radiography*,  surgery
Middle Aged
Nasopharyngeal Neoplasms / complications*,  pathology,  radiography*,  surgery
Neoplasm Invasiveness
Neoplasm Recurrence, Local / complications*,  pathology,  radiography,  surgery
Orbit / radiography*
Tomography, X-Ray Computed
Vision Disorders / etiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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