Document Detail


Visual function, fatty acids and dyslexia.
MedLine Citation:
PMID:  10970719     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
There is mounting evidence that developmental dyslexia is a neurodevelopmental disorder which involves abnormalities of fatty acid metabolism, particularly with respect to certain long-chain highly unsaturated fatty acids (HUFAs). Psychophysical evidence also strongly suggests that dyslexics may have visual deficits as well as phonological problems. Specifically, these visual deficits appear to be related to the magnocellular pathway, which is specialized for processing fast, rapidly-changing information about the visual scene. It remains unclear how these two aspects of dyslexia - fatty acid processing and visual magnocellular function - could be related. We propose some hypotheses - necessarily speculative, given the paucity of biochemical research in this field to date - which address this question.
Authors:
K E Taylor; A J Richardson
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Prostaglandins, leukotrienes, and essential fatty acids     Volume:  63     ISSN:  0952-3278     ISO Abbreviation:  Prostaglandins Leukot. Essent. Fatty Acids     Publication Date:    2000 Jul-Aug
Date Detail:
Created Date:  2000-10-04     Completed Date:  2000-10-25     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8802730     Medline TA:  Prostaglandins Leukot Essent Fatty Acids     Country:  SCOTLAND    
Other Details:
Languages:  eng     Pagination:  89-93     Citation Subset:  IM    
Copyright Information:
Copyright 2000 Harcourt Publishers Ltd.
Affiliation:
University Laboratory of Physiology, Oxford, UK. kathleen.taylor@physiol.ox.au.uk
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MeSH Terms
Descriptor/Qualifier:
Brain / growth & development,  metabolism*
Cytoskeleton / metabolism
Dyslexia / etiology*,  genetics,  metabolism
Fatty Acids, Unsaturated / metabolism*
Humans
Lipid Bilayers
Neurons / immunology,  metabolism
Phospholipids / metabolism
Vision Disorders / etiology*
Visual Pathways / physiopathology*
Chemical
Reg. No./Substance:
0/Fatty Acids, Unsaturated; 0/Lipid Bilayers; 0/Phospholipids

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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