| Visual function, fatty acids and dyslexia. | |
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MedLine Citation:
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PMID: 10970719 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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There is mounting evidence that developmental dyslexia is a neurodevelopmental disorder which involves abnormalities of fatty acid metabolism, particularly with respect to certain long-chain highly unsaturated fatty acids (HUFAs). Psychophysical evidence also strongly suggests that dyslexics may have visual deficits as well as phonological problems. Specifically, these visual deficits appear to be related to the magnocellular pathway, which is specialized for processing fast, rapidly-changing information about the visual scene. It remains unclear how these two aspects of dyslexia - fatty acid processing and visual magnocellular function - could be related. We propose some hypotheses - necessarily speculative, given the paucity of biochemical research in this field to date - which address this question. |
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Authors:
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K E Taylor; A J Richardson |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: Prostaglandins, leukotrienes, and essential fatty acids Volume: 63 ISSN: 0952-3278 ISO Abbreviation: Prostaglandins Leukot. Essent. Fatty Acids Publication Date: 2000 Jul-Aug |
Date Detail:
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Created Date: 2000-10-04 Completed Date: 2000-10-25 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8802730 Medline TA: Prostaglandins Leukot Essent Fatty Acids Country: SCOTLAND |
Other Details:
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Languages: eng Pagination: 89-93 Citation Subset: IM |
Copyright Information:
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Copyright 2000 Harcourt Publishers Ltd. |
Affiliation:
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University Laboratory of Physiology, Oxford, UK. kathleen.taylor@physiol.ox.au.uk |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Brain
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growth & development,
metabolism* Cytoskeleton / metabolism Dyslexia / etiology*, genetics, metabolism Fatty Acids, Unsaturated / metabolism* Humans Lipid Bilayers Neurons / immunology, metabolism Phospholipids / metabolism Vision Disorders / etiology* Visual Pathways / physiopathology* |
| Chemical | |
Reg. No./Substance:
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0/Fatty Acids, Unsaturated; 0/Lipid Bilayers; 0/Phospholipids |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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