Document Detail

Visual evoked potentials in patients with psoriasis vulgaris.
MedLine Citation:
PMID:  11824655     Owner:  NLM     Status:  MEDLINE    
PURPOSE: The aim of this study is an estimation of the visual evoked potentials (VEP) in patients with psoriasis vulgaris. The role of the nervous system was pointed out in the pathogenesis of psoriasis. Also epidemiologic research confirms that patients with psoriasis are at increased risk of MS development. MATERIALS AND METHODS: A group of 30 psoriatic males aged between 18 and 54 was examined. The results were compared with those obtained from a group of 30 healthy age-matched males and they were correlated with the psoriasis area and severity index (PASI), the skin surface area involved, duration of the disease and duration of the last relapse. In neurological and ophthalmological examinations no pathological symptoms were detected in either group. The VEP examination was executed using pattern reversal (pr) and pattern flash (pf) stimulation. RESULTS: Using pf stimulation, in the group of patients with psoriasis vulgaris, a statistically significant elongation in the latency of P-100 and reduction of response amplitude, not related to the PASI, nor the skin surface area involved, nor duration of the last relapse, were observed. CONCLUSIONS: The results of the study indicate subclinical damage of the visual pathway in patients with psoriasis vulgaris.
A Grzybowski; G Grzybowski; A Druzdz; R Zaba
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Documenta ophthalmologica. Advances in ophthalmology     Volume:  103     ISSN:  0012-4486     ISO Abbreviation:  Doc Ophthalmol     Publication Date:  2001 Nov 
Date Detail:
Created Date:  2002-02-04     Completed Date:  2002-09-23     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370667     Medline TA:  Doc Ophthalmol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  187-94     Citation Subset:  IM    
Department of Ophthalmology, Karol Marcinkowski University School of Medical Sciences, Poznań, Poland.
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MeSH Terms
Evoked Potentials, Visual / physiology*
Middle Aged
Psoriasis / complications,  physiopathology*
Visual Pathways / physiopathology*

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