| Visual evoked potential is superior to triple dose magnetic resonance imaging in the diagnosis of optic nerve involvement. | |
| | |
MedLine Citation:
|
PMID: 15527206 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The aim of this study was to evaluate whether VEP is sensitive to optic neuritis (ON) when compared with triple dose orbital MRI. Twenty-four relapsing-remitting MS (RRMS) patients were included in the study. Group I (n = 10) patients with acute ON, Group II (n = 8): patients presenting with a current relapse who had the history of ON in the previous relapses. Group III (n = 6): patients presenting with a current relapse but with no history of ON. Neuro-ophtalmological evaluation. VEP investigation and orbital MRI with triple dose (0.3 mmol/kg) gadolinium (Gd) were carried out for all. VEP was found to be 70% sensitive and 12.5% specific to the acute ON, whereas orbital MRI with triple dose Gd was 70% sensitive and 100% specific. In chronic ON, the sensitivity of orbital MRI is 0%, whereas the VEP is still 75% sensitive to chronic optic nerve involvement and can distinguish the pathology 100% specifically. In conclusion, orbital MRI with triple dose Gd is not more sensitive than VEP in determining the acute optic nerve pathologies but it is a 100% specific method. The results suggest that VEP is superior to the orbital MRI in determining the chronic optic nerve involvement. |
| | |
Authors:
|
Göksemin Acar; Serkan Ozakbas; Handan Cakmakci; Fethi Idiman; Egemen Idiman |
Related Documents
:
|
11533536 - Trigeminal pain caused by a cerebellopontine-angle lipoma. case report and review of th... 9818836 - Is there a correlation between vascular loops and unilateral auditory symptoms? 18204776 - Clinics in diagnostic imaging (120). right rhinogenic optic neuritis secondary to mucoc... 17038036 - Isolated ocular motor nerve palsy in dural carotid-cavernous sinus fistula. 3775416 - Computed tomography of partial growth plate arrest: initial experience. 1523306 - Gastrointestinal bleeding: improved localization with cine scintigraphy. |
Publication Detail:
|
Type: Comparative Study; Journal Article |
Journal Detail:
|
Title: The International journal of neuroscience Volume: 114 ISSN: 0020-7454 ISO Abbreviation: Int. J. Neurosci. Publication Date: 2004 Aug |
Date Detail:
|
Created Date: 2004-11-05 Completed Date: 2005-01-10 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 0270707 Medline TA: Int J Neurosci Country: United States |
Other Details:
|
Languages: eng Pagination: 1025-33 Citation Subset: IM |
Affiliation:
|
Departments of Neurology and Radiodiagnostics Medical School, Dokuz Eylül University, Izmir, Turkey. goksemind@yahoo.com |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Evoked Potentials, Visual / physiology* Female Gadolinium / diagnostic use Humans Magnetic Resonance Imaging* Male Multiple Sclerosis / physiopathology* Neurologic Examination Optic Nerve / pathology, physiopathology Optic Neuritis / diagnosis*, etiology |
| Chemical | |
Reg. No./Substance:
|
7440-54-2/Gadolinium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Electrophysiological and quantitative electroencephalographic measurements after treatment by transc...
Next Document: Lithium ion "cyclotron resonance" magnetic fields decrease seizure onset times in lithium-pilocarpin...