Document Detail

Visual evoked potential: a diagnostic tool for the assessment of hepatic encephalopathy.
MedLine Citation:
PMID:  6421664     Owner:  NLM     Status:  MEDLINE    
Visual evoked potential recordings were examined in 45 liver cirrhosis patients with (n = 29) and without (n = 16) encephalopathy, in 15 normal volunteers, and in one patient with an opioid induced stupor state. Visual evoked potential parameters were classified on the basis of EEG recordings. Plasma concentrations of amino acids, octopamine, and ammonia were assayed in order to document the metabolic change of hepatic encephalopathy. Latencies and wave patterns recorded after flash stimulation differentiated the four degrees of the coma one from another according to EEG classification in the 29 patients with encephalopathy. In the group of 16 patients without clinical and EEG evidence of encephalopathy the visual potential recordings discriminated a group of patients (n = 10) in a preclinical stage of encephalopathy. Biochemical parameters and subsequent clinical observation of patients confirmed our judgement of a preclinical stage of encephalopathy. These results suggest that visual evoked potentials are a simple, suitable and objective method for differentiating the degrees of encephalopathy and for identifying the preclinical stage of encephalopathy.
M L Zeneroli; G Pinelli; G Gollini; A Penne; E Messori; G Zani; E Ventura
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Gut     Volume:  25     ISSN:  0017-5749     ISO Abbreviation:  Gut     Publication Date:  1984 Mar 
Date Detail:
Created Date:  1984-03-30     Completed Date:  1984-03-30     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  2985108R     Medline TA:  Gut     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  291-9     Citation Subset:  AIM; IM    
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MeSH Terms
Amino Acids, Essential / blood
Ammonia / blood
Evoked Potentials, Visual*
Hepatic Encephalopathy / blood,  diagnosis*,  physiopathology
Liver Cirrhosis / blood,  physiopathology
Middle Aged
Octopamine / blood
Reg. No./Substance:
0/Amino Acids, Essential; 104-14-3/Octopamine; 7664-41-7/Ammonia

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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