| Visual LV motion and invasive LVdP/dtmax for selection and optimisation of cardiac resynchronisation therapy. | |
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MedLine Citation:
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PMID: 18958268 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Echocardiography shows that multiphasic septal movement and a septal to lateral apical systolic left ventricular (LV) motion have a high predictive value for dyssynchrony and the response to cardiac resynchronisation therapy (CRT). Presence of dyssynchrony is also the major marker for CRT response in the presence of scar tissue, provided the interventricular (V-V) pacing interval is optimalised. For atrioventricular (AV) interval optimisation, the velocity-time integral of the transmitral flow has an excellent correlation with invasive LVdP/dt(max). In acute haemodynamic measurements, LVdP/dt(max) shows strongly the effect of AV and V-V optimisation. It also illustrates that the haemodynamic effect of LV pacing when associated with intrinsic conduction over the right bundle is equal to or better than biventricular pacing. We found that once AV and V-V interval were optimised, QRS morphology could be used as a template for optimal therapy. Automated continuous optimisation of the pacing intervals will be the big challenge for the future. (Neth Heart J 2008;16(Suppl1):S32-S35.). |
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Authors:
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A H M Jansen; B M van Gelder |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation Volume: 16 ISSN: 1568-5888 ISO Abbreviation: Neth Heart J Publication Date: 2008 Oct |
Date Detail:
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Created Date: 2008-10-29 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101095458 Medline TA: Neth Heart J Country: Netherlands |
Other Details:
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Languages: eng Pagination: S32-5 Citation Subset: - |
Affiliation:
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Department of Cardiology, Catharina Hospital, Eindhoven, the Netherlands. |
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