Document Detail

Visceral perception thresholds after rectal thermal and pressure stimuli in irritable bowel syndrome patients.
MedLine Citation:
PMID:  14731129     Owner:  NLM     Status:  MEDLINE    
BACKGROUND AND AIM: Visceral hypersensitivity has been shown to be present in irritable bowel syndrome (IBS). The current study sought to compare the characteristics of visceral perception thresholds after rectal thermal and pressure stimuli between IBS patients and healthy subjects. METHODS: A total of 46 patients with IBS were diagnosed using Rome II criteria. Thirteen healthy individuals participated in the study. Rectal visceral perception thresholds were examined in patients with IBS and in normal controls after thermal and pressure stimuli. Subjects were asked to report the sensation type, location, and spread. RESULTS: Compared with healthy subjects, IBS patients demonstrated significantly initially lower perception thresholds and defecation thresholds to rectal thermal and pressure stimuli, particularly in patients with diarrhea-predominant IBS. Ice stimuli on the abdominal wall had varied effects on symptoms in patients with IBS and did not affect perception thresholds. CONCLUSIONS: Visceral perception thresholds were decreased significantly after rectal thermal and pressure stimuli in patients with IBS. Visceral hypersensitivity may be one of the important pathogenic mechanisms in IBS.
Yanqing Li; Yanmei Wang; Xiuli Zuo; Yuting Guo; Haiyan Zhang; Xuefeng Lu; Junman Li; Paul V Desmond
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of gastroenterology and hepatology     Volume:  19     ISSN:  0815-9319     ISO Abbreviation:  J. Gastroenterol. Hepatol.     Publication Date:  2004 Feb 
Date Detail:
Created Date:  2004-01-20     Completed Date:  2004-05-21     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8607909     Medline TA:  J Gastroenterol Hepatol     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  187-91     Citation Subset:  IM    
Department of Gastroenterology, Qilu Hospital of Shandong University, Jinan, China.
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MeSH Terms
Constipation / etiology,  physiopathology
Diarrhea / etiology,  physiopathology
Irritable Bowel Syndrome / physiopathology*
Physical Stimulation
Rectum / physiopathology*
Sensory Thresholds*
Viscera / physiopathology*

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