Document Detail

Visceral leishmaniasis in immunosuppressed Caucasian patient.
MedLine Citation:
PMID:  22605859     Owner:  NLM     Status:  MEDLINE    
A 64-year-old man was admitted with fever, weight loss, fatigue and night sweats. He was known to have rheumatoid arthritis and had been taking methotrexate for 1 year. He had worked in Saudi Arabia until 1994 and had been living in Spain for 6 months every year. Clinical examination showed an enlarged spleen. Routine investigations showed pancytopaenia. Serial blood cultures were negative. CT scan confirmed splenomegaly and was otherwise unremarkable. Bone marrow biopsy revealed Leishmania amastigote consistent with a diagnosis of visceral leishmaniasis. After discussing with the hospital for tropical diseases (HTD), he was started on liposomal amphotericin B. Following two infusions of amphotericin B, he started improving as his fever, night sweats and weakness had settled. He was then discharged and followed up in HTD clinic 4 weeks later where he was found to be consistently improving.
Muhammad Toqeer; Nadeem Rahman; Mark W Whitehead; Diana Lockwood
Related Documents :
22724879 - Intra-articular injection of autologous mesenchymal stem cells in six patients with kne...
24047869 - Racial disparities in knee and hip total joint arthroplasty: an 18-year analysis of nat...
11095439 - Two-year follow-up of acromegalic patients treated with slow release lanreotide (30 mg).
11124859 - Markers of tumor invasion are major predictive factors for the long-term outcome of cor...
24226489 - Immediate postoperative and mid-term survival in nonagenarians undergoing non-traumatic...
8486199 - Long-acting injectable bromocriptine (parlodel lar) in the chronic treatment of prolact...
24767229 - Long-term comparison using ex-press glaucoma shunt in black and white patients.
105739 - Long-term chrysotherapy in rheumatoid arthritis.
24696069 - Monitoring treatment of field cancerisation with 3% diclofenac sodium 2.5% hyaluronic a...
Publication Detail:
Type:  Case Reports; Journal Article     Date:  2012-05-08
Journal Detail:
Title:  BMJ case reports     Volume:  2012     ISSN:  1757-790X     ISO Abbreviation:  BMJ Case Rep     Publication Date:  2012  
Date Detail:
Created Date:  2012-05-18     Completed Date:  2013-02-12     Revised Date:  2014-05-11    
Medline Journal Info:
Nlm Unique ID:  101526291     Medline TA:  BMJ Case Rep     Country:  England    
Other Details:
Languages:  eng     Pagination:  -     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Amphotericin B / therapeutic use*
Antiprotozoal Agents / therapeutic use*
Arthritis, Rheumatoid / complications
European Continental Ancestry Group
Leishmaniasis, Visceral / diagnosis*,  drug therapy*
Middle Aged
Tomography, X-Ray Computed
Reg. No./Substance:
0/Antiprotozoal Agents; 0/liposomal amphotericin B; 7XU7A7DROE/Amphotericin B

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Rosuvastatin-induced pemphigoid.
Next Document:  Ulcerative colitis presenting as acute infectious gastroenteritis with a paralytic ileus.