| Visceral leishmaniasis during pregnancy treated with meglumine antimoniate. | |
| | |
MedLine Citation:
|
PMID: 7499009 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Data on the efficacy and safety of pentavalent antimony in the treatment of visceral leishmaniasis during pregnancy are scanty. A case of visceral leishmaniasis in a 39-year-old woman in the second trimester of pregnancy is reported here. The patient was hospitalized in poor condition with high fever and pancytopenia which had lasted for 6 weeks. A bone marrow aspirate revealed numerous amastigotes and serodiagnosis for Leishmania was positive at a high titer. The patient was successfully treated with meglumine antimoniate at a daily dose of 850 mg of antimony for 20 days. She delivered at term a healthy female baby who remains in good condition at 18 months of age. Thus a dose of 850 mg of antimony, which is lower than that presently recommended, seems to be effective and non toxic to the fetus when administered at the second trimester of pregnancy. |
| | |
Authors:
|
R Utili; A Rambaldi; M F Tripodi; A Andreana |
Related Documents
:
|
20544869 - Sonographic diagnosis and successful medical management of an intramural ectopic pregna... 1533529 - Advancing conservative treatment of ectopic pregnancy--laparoscopic and "non-surgical" ... 320999 - Methotrexate uptake by psoriatic epidermis. 22223909 - Anaesthetic management for emergency caesarean section in a patient with an untreated r... 12797089 - Ectopic pregnancy treatment using pelviscopic or vaginosonographically-guided intrachor... 12198869 - Changes in alveolar morphology during open bite treatment and prediction of treatment r... 1095309 - Clinical trial of a low dose combined oral contraceptive ('ovranette'). 12432329 - Seventy-five ectopic pregnancies. medical and surgical management. 9485969 - The effect of position on autonomic nervous activity in late pregnancy. |
Publication Detail:
|
Type: Case Reports; Journal Article |
Journal Detail:
|
Title: Infection Volume: 23 ISSN: 0300-8126 ISO Abbreviation: Infection Publication Date: 1995 May-Jun |
Date Detail:
|
Created Date: 1996-01-18 Completed Date: 1996-01-18 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 0365307 Medline TA: Infection Country: GERMANY |
Other Details:
|
Languages: eng Pagination: 182-3 Citation Subset: IM |
Affiliation:
|
Institute of Medical Therapy, Faculty of Medicine, 2nd University of Naples, Italy. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Animals Antiprotozoal Agents / therapeutic use* Bone Marrow / parasitology Female Humans Infant, Newborn Leishmania infantum / isolation & purification Leishmaniasis, Visceral / drug therapy* Meglumine / therapeutic use* Organometallic Compounds / therapeutic use* Pregnancy Pregnancy Complications, Parasitic / drug therapy* Pregnancy Trimester, Second |
| Chemical | |
Reg. No./Substance:
|
0/Antiprotozoal Agents; 0/Organometallic Compounds; 133-51-7/meglumine antimoniate; 6284-40-8/Meglumine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Acute suppurative thyroiditis caused by Salmonella enteritidis.
Next Document: Uncomplicated central vein catheterization of high risk patients with real time ultrasound guidance.