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Visceral adiposity index, hypertriglyceridemic waist and risk of diabetes: the China Health and Nutrition Survey 2009.
MedLine Citation:
PMID:  24048141     Owner:  NLM     Status:  Publisher    
Background:The visceral adiposity index (VAI) and hypertriglyceridemic waist phenotype (the simultaneous presence of waist circumference [WC]90/80 cm for men/women and plasma triglyceride [TG] concentration1.7 mmol/l for both genders) have been identified as good indicators of visceral adiposity, which is an independent risk factor for diabetes. Chinese populations are characterized by a predominance of visceral fat accumulation despite having comparatively low weight. The two surrogate markers of visceral adiposity might effectively identify Chinese adults at diabetes risk. We aimed to examine the association between the VAI and risk for diabetes or between the hypertriglyceridemic waist phenotype and diabetes risk.Methods:We conducted a cross-sectional analysis of 7639 Chinese men and women aged 18 years using data from the China Health and Nutrition Survey 2009. Logistic regression was used to evaluate the associations.Results:For men, compared with participants in the lowest quartile of VAI scores, the multivariable-adjusted odds ratios (ORs) (with 95% confidence intervals) for diagnosed diabetes were 1.1 (0.7-1.7), 1.9 (1.3-2.8), and 3.6 (2.5-5.3) for those in the second, third, and top quartile of VAI scores, respectively. For women, the corresponding figures were 0.9 (0.5-1.4), 1.7 (1.1-2.6), and 2.8 (1.9-4.2), respectively. The multivariate-adjusted ORs (with 95% confidence intervals) for diabetes in men with the hypertriglyceridemic waist phenotype compared with men with both WC and TG measurements below the defined cut points were 3.7 (2.6-5.4). For women, the corresponding figure was 3.7 (2.4-5.5). For both men and women, the associations between the 4th quartile of VAI scores and risk of diabetes or between the hypertriglyceridemic waist phenotype and risk of diabetes were consistently seen in various subgroups.Conclusion:Among Chinese adults, high VAI scores and the hypertriglyceridemic waist phenotype are strongly associated with diabetes risk.International Journal of Obesity accepted article preview online, 19 September 2013. doi:10.1038/ijo.2013.181.
T Du; X Sun; R Huo; X Yu
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-9-19
Journal Detail:
Title:  International journal of obesity (2005)     Volume:  -     ISSN:  1476-5497     ISO Abbreviation:  Int J Obes (Lond)     Publication Date:  2013 Sep 
Date Detail:
Created Date:  2013-9-19     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101256108     Medline TA:  Int J Obes (Lond)     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Department of Endocrinology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
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