Document Detail


Visceral Blood Flow Modulation: Potential Therapy for Morbid Obesity.
MedLine Citation:
PMID:  23381772     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
We present this preliminary investigation into the safety and feasibility of endovascular therapy for morbid obesity in a swine model. A flow-limiting, balloon-expandable covered stent was placed in the superior mesenteric artery of three Yorkshire swine after femoral arterial cutdown. The pigs were monitored for between 15 and 51 days after the procedure and then killed, with weights obtained at 2-week increments. In the two pigs in which the stent was flow limiting, a reduced rate of weight gain (0.42 and 0.53 kg/day) was observed relative to the third pig (0.69 kg/day), associated with temporary food aversion and signs of mesenteric ischemia in one pig.
Authors:
Tyler J Harris; Timothy P Murphy; Bryan S Jay; Christopher O Hampson; Abdul M Zafar
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-2-5
Journal Detail:
Title:  Cardiovascular and interventional radiology     Volume:  -     ISSN:  1432-086X     ISO Abbreviation:  Cardiovasc Intervent Radiol     Publication Date:  2013 Feb 
Date Detail:
Created Date:  2013-2-5     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8003538     Medline TA:  Cardiovasc Intervent Radiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Vascular and Interventional Radiology, University of California, Los Angeles, 757 Westwood Blvd., Suite 1638, Los Angeles, CA, 90095-7437, USA, tjharris@gmail.com.
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