Document Detail


Viruses and apoptosis.
MedLine Citation:
PMID:  7749317     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Apoptosis is an active process of cell death that serves diverse functions in multicellular organisms, and under physiological conditions, it is tightly controlled. Many virus genomes encode gene products that modulate apoptosis, either positively or negatively, and induction of apoptosis often contributes directly to the cytopathogenic effects of the viruses. Inhibition of apoptosis by viruses, on the other hand, may prevent premature death of infected cells, thereby facilitating viral replication, spread, or persistence.
Authors:
Y Shen; T E Shenk
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.; Review    
Journal Detail:
Title:  Current opinion in genetics & development     Volume:  5     ISSN:  0959-437X     ISO Abbreviation:  Curr. Opin. Genet. Dev.     Publication Date:  1995 Feb 
Date Detail:
Created Date:  1995-06-20     Completed Date:  1995-06-20     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  9111375     Medline TA:  Curr Opin Genet Dev     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  105-11     Citation Subset:  IM    
Affiliation:
Howard Hughes Medical Institute, Department of Molecular Biology, Princeton University, New Jersey 08544-1014, USA.
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MeSH Terms
Descriptor/Qualifier:
Adenoviridae / physiology*
Animals
Apoptosis*
Baculoviridae / physiology*
Herpesvirus 4, Human / physiology*
Humans
Grant Support
ID/Acronym/Agency:
CA41086/CA/NCI NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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