Document Detail


Virus-mimicking nano-constructs as a contrast agent for near infrared photoacoustic imaging.
MedLine Citation:
PMID:  23334567     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
We report the first proof-of-principle demonstration of photoacoustic imaging using a contrast agent composed of a plant virus protein shell, which encapsulates indocyanine green (ICG), the only FDA-approved near infrared chromophore. These nano-constructs can provide higher photoacoustic signals than blood in tissue phantoms, and display superior photostability compared to non-encapsulated ICG. Our preliminary results suggest that the constructs do not elicit an acute immunogenic response in healthy mice.
Authors:
Sharad Gupta; Muhammad R Chatni; Ayala L N Rao; Valentine I Vullev; Lihong V Wang; Bahman Anvari
Related Documents :
23335657 - Ultrasound-guided characterization of interstitial ablated tissue using rf time series:...
20006707 - Non-viral nanosystems for systemic sirna delivery.
23110677 - Cascaded discrimination of normal, abnormal, and confounder classes in histopathology: ...
9929197 - Mobile workers in healthcare and their information needs: are 2-way pagers the answer?
15009857 - Electroanatomic mapping of the right atrium with a right atrial basket catheter and thr...
20363677 - A statistical pixel intensity model for segmentation of confocal laser scanning microsc...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-21
Journal Detail:
Title:  Nanoscale     Volume:  -     ISSN:  2040-3372     ISO Abbreviation:  Nanoscale     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101525249     Medline TA:  Nanoscale     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Bioengineering, University of California, Riverside, Riverside, CA 92521, USA. anvarib@ucr.edu.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  New insights regarding gonad development in European eel: evidence for a direct ovarian differentiat...
Next Document:  Haematotoxicity of Integrated Textile Mill Effluent to an Air-Breathing Fish Heteropneustes fossilis...