Document Detail


Virus-like particles and macromolecules in human milk and breast tumors.
MedLine Citation:
PMID:  92388     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Relevant data pertaining to present evidence for virus-like particles and virus-related macromolecules in human milk and breast tumors are presented. A critical review and discussion of reported observations concerning virus-related macromolecules will include RNA-directed DNA polymerase, viral antigens, and RNA related to murine mammary tumor virus and/or Mason-Pfizer monkey virus. From the standpoint of clinical applications, the finding of viral-related antigens in human breast tumors and evidence for specific host immune responses to one or more of these antigens may be especially pertinent. The latter data, therefore, will be discussed in depth as to possible employment of these parameters in diagnosis, prognosis and possible management of the human disease.
Authors:
A S Dion
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  CRC critical reviews in clinical laboratory sciences     Volume:  11     ISSN:  0590-8191     ISO Abbreviation:  CRC Crit Rev Clin Lab Sci     Publication Date:  1979 Dec 
Date Detail:
Created Date:  1980-02-15     Completed Date:  1980-02-15     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  1247734     Medline TA:  CRC Crit Rev Clin Lab Sci     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  245-70     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Antigens, Viral
Breast Neoplasms / enzymology,  immunology,  microbiology*
DNA-Directed DNA Polymerase / metabolism
Female
Haplorhini
Humans
Immunity
Immunity, Cellular
Mammary Neoplasms, Experimental / microbiology
Mammary Tumor Virus, Mouse / metabolism,  ultrastructure
Mice
Milk, Human / enzymology,  microbiology*
Pregnancy
RNA, Neoplasm / analysis
RNA-Directed DNA Polymerase / analysis
Viral Proteins / analysis
Viruses / isolation & purification*
Chemical
Reg. No./Substance:
0/Antigens, Viral; 0/RNA, Neoplasm; 0/Viral Proteins; EC 2.7.7.49/RNA-Directed DNA Polymerase; EC 2.7.7.7/DNA-Directed DNA Polymerase

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