| Virulence factors profile of drug-resistant Escherichia coli isolates from urinary tract infections in Punjab, Pakistan. | |
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MedLine Citation:
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PMID: 20814711 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Escherichia coli is considered to be the main causative agent of urinary tract infections (UTIs). The primary objective of this study was to investigate the spectrum of five virulence factors among drug-resistant clinical E. coli isolates associated with pyelonephritis and cystitis. A total of 101 samples were positive for E. coli (42 from pyelonephritis cases and 59 from cystitis cases) out of 457 urine samples of patients. Among toxins, haemolysin and secreted autotransporter toxin are found more frequently in isolates causing pyelonephritis (p < 0.020) than cystitis (p < 0.083). The frequent occurrence of P-pili, S-fimbria and protein involved in intestinal colonisation was noted among E. coli isolates associated with pyelonephritis. Overall, the study suggests that clinical isolates associated with pyelonephritis are more virulent than those associated with cystitis and diversified association with various antimicrobial resistance phenotypes was noted. |
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Authors:
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M Idress; U Mussarat; Y Badshah; R Qamar; H Bokhari |
Publication Detail:
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Type: Journal Article Date: 2010-09-03 |
Journal Detail:
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Title: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology Volume: 29 ISSN: 1435-4373 ISO Abbreviation: Eur. J. Clin. Microbiol. Infect. Dis. Publication Date: 2010 Dec |
Date Detail:
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Created Date: 2010-12-01 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8804297 Medline TA: Eur J Clin Microbiol Infect Dis Country: Germany |
Other Details:
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Languages: eng Pagination: 1533-7 Citation Subset: IM |
Affiliation:
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Department of Biosciences, COMSATS Institute of Information Technology, Chak Shazad Campus, Park Road, Islamabad, Pakistan. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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