| Virtual colonoscopy with magnetic resonance imaging: in vitro evaluation of a new concept. | |
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MedLine Citation:
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PMID: 9178678 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND & AIMS: Screening for colonic polyps is desirable. A new concept based on cross-sectional and endoscopic analysis of a magnetic resonance (MR) data set is presented. METHODS: Ex vivo autopsy colonic specimens, containing artificially placed polyps, were obtained and filled with a gadolinium-containing solution. Forty-four thin-section MR images were obtained in a 1.5-T MR scanner in 28 seconds. A three-dimensional endoscopic fly-through of these images was rendered. Fly-throughs and two-dimensional cross-sectional images were analyzed by two observers for the presence of polyps. RESULTS: The average sensitivity and specificity for the detection of polyps based on three-dimensional endoscopic MR colon imaging were 87% and 96%, respectively. Analysis of cross-sectional images showed an overall sensitivity and specificity of merely 57% and 84%, respectively. The difference in the interpretation of three-dimensional MR colonoscopy and two-dimensional cross-sections was statistically significant (P < 0.001). With three-dimensional MR colonoscopy, overall sensitivity for detection of polyps measuring < or =5 mm in length and diameter was 70%; for larger polyps, it increased to 95% (P < 0.01). CONCLUSIONS: The feasibility of an MR-based endoluminal assessment of the colon is shown. Minimal invasiveness, lack of radiation exposure, and high in vitro diagnostic accuracy warrant further investigation of this novel concept. |
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Authors:
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A W Schoenenberger; P Bauerfeind; G P Krestin; J F Debatin |
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Publication Detail:
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Type: In Vitro; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Gastroenterology Volume: 112 ISSN: 0016-5085 ISO Abbreviation: Gastroenterology Publication Date: 1997 Jun |
Date Detail:
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Created Date: 1997-07-21 Completed Date: 1997-07-21 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0374630 Medline TA: Gastroenterology Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1863-70 Citation Subset: AIM; IM |
Affiliation:
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Department of Medical Radiology, University Hospital Zürich, Switzerland. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Colonic Polyps
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pathology* Colonoscopy Humans Image Processing, Computer-Assisted Magnetic Resonance Imaging |
| Comments/Corrections | |
Comment In:
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Gastroenterology. 1997 Jun;112(6):2150-2
[PMID:
9178714
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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