Document Detail

Virtual Histology Analysis of Carotid Atherosclerotic Plaque: Plaque Composition at the Minimum Lumen Site and of the Entire Carotid Plaque.
MedLine Citation:
PMID:  23194195     Owner:  NLM     Status:  Publisher    
BACKGROUND: Virtual Histology intravascular ultrasound (VH IVUS) volumetric analysis (analysis of the entire plaque responsible for stenosis) has been used for carotid plaque diagnosis. Knowing the carotid plaque characteristics by analyzing the plaque composition only at the minimum lumen site will facilitate plaque diagnosis using VH IVUS. PURPOSE: To detect the relationship between the VH IVUS volumetric analysis of the entire plaque responsible for carotid artery stenosis and the VH IVUS cross-section plaque analysis at the minimum lumen site. METHODS: Forty-eight atherosclerotic cervical carotid stenoses in 45 consecutive patients were included in the study. VH IVUS was obtained during the carotid artery stenting procedure. RESULTS: Simple regression analysis revealed that the volumetric proportion of each plaque type correlated significantly with the corresponding plaque-type area at the minimum lumen site. The adjusted coefficients of determination of the simple regression analyses were .782 (P < .001) for fibrous tissue, .741 (P < .001) for fibrofatty tissue, .864 (P < .001) for dense calcium, and .918 (P < .001) for necrotic core. CONCLUSION: The plaque composition at the minimum lumen site represents the volumetric composition of the entire carotid plaque that causes atherosclerotic cervical carotid artery stenosis.
Arihito Tsurumi; Yuko Tsurumi; Osamu Hososhima; Noriaki Matsubara; Takashi Izumi; Shigeru Miyachi
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-11-29
Journal Detail:
Title:  Journal of neuroimaging : official journal of the American Society of Neuroimaging     Volume:  -     ISSN:  1552-6569     ISO Abbreviation:  J Neuroimaging     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-30     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9102705     Medline TA:  J Neuroimaging     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 by the American Society of Neuroimaging.
From the Department of Neurosurgery, National Hospital Organization Nagoya Medical Center, Nagoya, Japan (AT); Department of Neurosurgery, Japanese Red Cross Nagoya Daiichi Hospital, Nagoya, Japan (YT); Department of Neurosurgery, Tosei General Hospital, Seto, Japan (OH); Department of Neurosurgery, Nagoya University Graduate School of Medicine, Nagoya, Japan (NM, TI, SM).
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