| The Virtual Cell: a software environment for computational cell biology. | |
| | |
MedLine Citation:
|
PMID: 11587765 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The newly emerging field of computational cell biology requires software tools that address the needs of a broad community of scientists. Cell biological processes are controlled by an interacting set of biochemical and electrophysiological events that are distributed within complex cellular structures. Computational modeling is familiar to researchers in fields such as molecular structure, neurobiology and metabolic pathway engineering, and is rapidly emerging in the area of gene expression. Although some of these established modeling approaches can be adapted to address problems of interest to cell biologists, relatively few software development efforts have been directed at the field as a whole. The Virtual Cell is a computational environment designed for cell biologists as well as for mathematical biologists and bioengineers. It serves to aid the construction of cell biological models and the generation of simulations from them. The system enables the formulation of both compartmental and spatial models, the latter with either idealized or experimentally derived geometries of one, two or three dimensions. |
| | |
Authors:
|
L M Loew; J C Schaff |
Related Documents
:
|
18835895 - The role of extracellular matrix in glioma invasion: a cellular potts model approach. 8013395 - The use of cell proliferation data in modeling of skin carcinogenesis. 19797295 - Dynamic alterations in chemokine gradients induce transendothelial shuttling of human t... 12153315 - Immobilized particles in gel matrix-type porous media. nonhomogeneous cell distribution. 1479045 - Cytoblock preparations for examination of cervical and other cells. 12818565 - Effects of cccp-induced mitochondrial uncoupling and cyclosporin a on cell volume, cell... |
Publication Detail:
|
Type: Journal Article; Research Support, U.S. Gov't, P.H.S.; Review |
Journal Detail:
|
Title: Trends in biotechnology Volume: 19 ISSN: 0167-7799 ISO Abbreviation: Trends Biotechnol. Publication Date: 2001 Oct |
Date Detail:
|
Created Date: 2001-10-05 Completed Date: 2002-01-03 Revised Date: 2009-11-19 |
Medline Journal Info:
|
Nlm Unique ID: 8310903 Medline TA: Trends Biotechnol Country: England |
Other Details:
|
Languages: eng Pagination: 401-6 Citation Subset: IM |
Affiliation:
|
Center for Biomedical Imaging Technology, Department of Physiology, University of Connecticut Health Center, Farmington, Connecticut 06030, USA. les@volt.uchc.edu |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Biology
/
trends* Cell Biology / trends* Computer Simulation* Models, Biological* Software |
| Grant Support | |
ID/Acronym/Agency:
|
RR13186/RR/NCRR NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: The 'biodrug' concept: an innovative approach to therapy.
Next Document: RNase P: from biological function to biotechnological applications.