Document Detail


Viral nanoparticles, noble metal decorated viruses and their nanoconjugates.
MedLine Citation:
PMID:  24836299     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Virus-based nanotechnology has generated interest in a number of applications due to the specificity of virus interaction with inorganic and organic nanoparticles. A well-defined structure of virus due to its multifunctional proteinaceous shell (capsid) surrounding genomic material is a promising approach to obtain nanostructured materials. Viruses hold great promise in assembling and interconnecting novel nanosized components, allowing to develop organized nanoparticle assemblies. Due to their size, monodispersity, and variety of chemical groups available for modification, they make a good scaffold for molecular assembly into nanoscale devices. Virus based nanocomposites are useful as an engineering material for the construction of smart nanoobjects because of their ability to associate into desired structures including a number of morphologies. Viruses exhibit the characteristics of an ideal template for the formation of nanoconjugates with noble metal nanoparticles. These bioinspired systems form monodispersed units that are highly amenable through genetic and chemical modifications. As nanoscale assemblies, viruses have sophisticated yet highly ordered structural features, which, in many cases, have been carefully characterized by modern structural biological methods. Plant viruses are increasingly being used for nanobiotechnology purposes because of their relative structural and chemical stability, ease of production, multifunctionality and lack of toxicity and pathogenicity in animals or humans. The multifunctional viruses interact with nanoparticles and other functional additives to the generation of bioconjugates with different properties - possible antiviral and antibacterial activities.
Authors:
Ignác Capek
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Publication Detail:
Type:  REVIEW     Date:  2014-4-25
Journal Detail:
Title:  Advances in colloid and interface science     Volume:  -     ISSN:  1873-3727     ISO Abbreviation:  Adv Colloid Interface Sci     Publication Date:  2014 Apr 
Date Detail:
Created Date:  2014-5-19     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8706645     Medline TA:  Adv Colloid Interface Sci     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2014. Published by Elsevier B.V.
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