| Viral molecular characterization of the first congenital rubella syndrome case in Vietnam. | |
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MedLine Citation:
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PMID: 21755831 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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BACKGROUND: Rubella virus (RV) infection during the first trimester of pregnancy often leads to severe birth defects known as congenital rubella syndrome (CRS). METHODS: A premature newborn male was clinically diagnosed as CRS with cataracts, congenital heart defects, microcephaly, hepatosplenomegaly, and thrombocytopenia. The infection was confirmed serologically and molecularly. RESULTS: The RV was characterized and clustered with the 2B genotype. CONCLUSIONS: The integrated description of clinical features, serological and molecular data provide a baseline for diagnosis and control of rubella and CRS in Vietnam. This is the first report of molecular investigation of wildtype RV strain in Vietnam, thus contributing to the documentation of RV's worldwide distribution. |
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Authors:
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Dinh Nguyen Tran; Minh Phuc Vu; Manh Tuan Ha; Tran Phuong Linh Giang; Katsuhiro Komase; Masashi Mizuguchi; Hiroshi Ushijima |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Clinical laboratory Volume: 57 ISSN: 1433-6510 ISO Abbreviation: Clin. Lab. Publication Date: 2011 |
Date Detail:
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Created Date: 2011-07-15 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9705611 Medline TA: Clin Lab Country: Germany |
Other Details:
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Languages: eng Pagination: 397-401 Citation Subset: IM |
Affiliation:
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Department of Developmental Medical Sciences, School of International Health, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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